4-(1-ethyl-1-methyl-propyl)-morpholine | 67061-40-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 恶嗪烷类
• 英文名称: 4-(1-ethyl-1-methyl-propyl)-morpholine
• 英文别名: N-(3-methyl-pent-3-yl)-morpholine；InChI=1/C10H21NO/c1-4-10(3,5-2)11-6-8-12-9-7-11/h4-9H2,1-3H；4-(3-methylpentan-3-yl)morpholine
• CAS: 67061-40-9
• 化学式: C₁₀H₂₁NO
• 分子量: 171.283
• InChiKey: LTXVFMPWDQPMMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• Therapeutic Agents
  申请人：Giordanetto Fabrizio

  公开号：US20080051405A1

  公开（公告）日：2008-02-28

  The present invention provides compounds of formula I, processes for preparing such compounds, their use in the treatment of obesity, psychiatric disorders, cognitive disorders, memory disorders, schizophrenia, epilepsy, and related conditions, type II diabetes, Metabolic syndrome and neurological disorders such as dementia, multiple sclerosis, Parkinson's disease, Huntington's chorea, Alzheimer's disease, and pain related disorders, and to pharmaceutical compositions containing them.

  本发明提供了公式I的化合物，制备这些化合物的方法，它们在治疗肥胖、精神障碍、认知障碍、记忆障碍、精神分裂症、癫痫以及相关疾病、2型糖尿病、代谢综合征和神经系统疾病如痴呆症、多发性硬化症、帕金森病、亨廷顿舞蹈症、阿尔茨海默病和与疼痛相关的疾病中的用途，以及含有它们的药物组合物。
• MOLECULARLY IMPRINTED POLYMERS, METHODS FOR THEIR PRODUCTION AND USES THEREOF
  申请人：Hearn Milton T.W.

  公开号：US20120225962A1

  公开（公告）日：2012-09-06

  The present invention relates to methods of preparing molecularly imprinted polymers (MIPs) which facilitate chemical hydrolysis and more particularly the hydrolysis of chemical substrates which possess hydrolytically labile bonds such as peptides and proteins. The present invention is thus directed to MIPs designed to possess hydrolytic activity, methods for preparing such MIPs and uses of the MIPs.

  本发明涉及制备分子印迹聚合物（MIPs）的方法，该方法促进化学水解，更具体地，促进具有水解敏感键的化学底物（例如肽和蛋白质）的水解。因此，本发明针对设计具有水解活性的MIPs，制备这种MIPs的方法以及MIPs的用途。
• Quinazoline derivatives
  申请人：Kitano Yasunori

  公开号：US20070265260A1

  公开（公告）日：2007-11-15

  A compound of the formula (I) or a pharmaceutically acceptable salt thereof, a hydrate thereof, a solvate thereof, an optically active compound thereof, a racemate thereof or a diastereomer mixture thereof has a superior tyrosine-specific protein kinase inhibitory activity and is useful as a pharmaceutical agent, particularly as an agent for the prophylaxis or treatment of various cancers, psoriasis or diseases caused by arteriosclerosis, and the like.

  化合物(I)的配方或其药学上可接受的盐、水合物、溶剂合物、其光学活性化合物、其外消旋体混合物或其差向异构体混合物具有优越的酪氨酸特异性蛋白激酶抑制活性，并可用作药物制剂，特别是用作预防或治疗各种癌症、银屑病或动脉硬化引起的疾病等的药物。
• ANTI-PROLIFERATIVE COMPOUNDS DERIVING FROM A 3-ARYL-COUMARINE OR 3-ARYL-QUINOLIN-2-ONE AND USES THEREOF
  申请人：EOS - Ethical Oncology Science S.p.A.

  公开号：EP2021333B1

  公开（公告）日：2010-07-14
• Molecular Chaperone Function Regulator
  申请人：Suzuki Tsuyoshi

  公开号：US20080200433A1

  公开（公告）日：2008-08-21

  According to the present invention, a molecular chaperone function regulator containing a quinazoline derivative represented by the following formula (I) wherein each symbol is as defined in Claims, or a pharmaceutically acceptable salt thereof, a hydrate or solvate thereof, an optically active form or racemate thereof or a diastereomer mixture thereof as an active ingredient can be provided.

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