5-formyl-5,6,7,8-tetrahydrohomofolic acid | 96482-98-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 5-formyl-5,6,7,8-tetrahydrohomofolic acid
• 英文别名: 2-[[4-[2-(2-Amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)ethylamino]benzoyl]amino]pentanedioic acid；2-[[4-[2-(2-amino-5-formyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl)ethylamino]benzoyl]amino]pentanedioic acid
• CAS: 96482-98-3
• 化学式: C₂₁H₂₅N₇O₇
• 分子量: 487.472
• InChiKey: GOPPVQOEWUBPLM-UHFFFAOYSA-N

物化性质

• 密度：
  1?+-.0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.9
• 重原子数：
  35
• 可旋转键数：
  10
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  216
• 氢给体数：
  7
• 氢受体数：
  10

反应信息

• 作为产物：
  描述：

  Homofolsaeure 、 甲酸 在 二甲胺基甲硼烷 作用下， 生成 5-formyl-5,6,7,8-tetrahydrohomofolic acid
  参考文献：
  名称：

  A new one-step synthesis of leucovorin from folic acid and of 5-formyl-5,6,7,8-tetrahydrohomofolic acid from homofolic acid using dimethylamine-borane in formic acid

  摘要：

  DOI：

  10.1021/jo00214a037

文献信息

• PEPTIDOMIMETIC MODULATORS OF CELL ADHESION
  申请人：Gour J. Barbara

  公开号：US20080081831A1

  公开（公告）日：2008-04-03

  Peptidomimetics of cyclic peptides, and compositions comprising such peptidomimetics are provided. The peptidomimetics have a three-dimensional structure that is substantially similar to a three-dimensional structure of a cyclic peptide that comprises a cadherin cell adhesion recognition sequence HAV. Methods for using such peptidomimetics for modulating cadherin-mediated cell adhesion in a variety of contexts are also provided.
• Bmp Gene and Fusion Protein
  申请人：Hidaka Chisa

  公开号：US20080260829A1

  公开（公告）日：2008-10-23

  This invention relates to BMP fusion genes, BMP fusion proteins. The invention further relates to methods for treatment using BMP fusion genes and BMP fusion proteins. Additionally, the invention relates to BMP fusion gene and BMP fusion protein pharmaceutical compositions.
• US7268115B2
  申请人：——

  公开号：US7268115B2

  公开（公告）日：2007-09-11
• US7446120B2
  申请人：——

  公开号：US7446120B2

  公开（公告）日：2008-11-04
• A new one-step synthesis of leucovorin from folic acid and of 5-formyl-5,6,7,8-tetrahydrohomofolic acid from homofolic acid using dimethylamine-borane in formic acid
  作者：Ronald A. Forsch、Andre Rosowsky

  DOI：10.1021/jo00214a037

  日期：1985.7