glycine-N-hydroxyl-N-methylamide hydrochloride | 3079-69-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: glycine-N-hydroxyl-N-methylamide hydrochloride
• 英文别名: 2-amino-N-hydroxy-N-methylacetamide hydrochloride；2-amino-N-hydroxy-N-methylacetamide;hydrochloride
• CAS: 3079-69-4
• 化学式: C₃H₈N₂O₂*ClH
• 分子量: 140.57
• InChiKey: CKHBWNKMNQKOAK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.79
• 重原子数：
  8
• 可旋转键数：
  1
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  66.6
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  glycine-N-hydroxyl-N-methylamide hydrochloride 、 {[4-(4-Carboxymethoxy-phenylazo)-benzoyl]-carboxymethyl-amino}-acetic acid 在 1-羟基苯并三唑 、 三乙胺 、 N,N'-二环己基碳二亚胺 作用下， 以52%的产率得到4-[4-({[(Hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methoxy)-phenylazo]-N,N-bis-({[(hydroxy-methyl-carbamoyl)-methyl]-carbamoyl}-methyl)-benzamide
  参考文献：
  名称：

  Synthesis of a novel azobenzene-based trihydroxamate siderophore and photoregulation of its ferric complex structure

  摘要：

  In order to develop an artificial photoresponsive siderophore by utilizing the photo-isomerization of an azobenzene group, a novel trihydroxamate siderophore based on an azobenzene skeleton was synthesized. The 1:1 and 2:2 stoichiometry of the ferric complex can be almost perfectly regulated reversibly by irradiation with UV and visible light, respectively. (C) 2000 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(00)00175-1