Chlor-bis-<3-fluor-phenyl>-phosphin | 23039-98-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Chlor-bis-<3-fluor-phenyl>-phosphin
• 英文别名: bis(3-fluorophenyl)-phosphinous chloride；Chloro-bis(3-fluorophenyl)phosphane
• CAS: 23039-98-7
• 化学式: C₁₂H₈ClF₂P
• 分子量: 256.619
• InChiKey: VVYHBYDZSHEDRU-UHFFFAOYSA-N

物化性质

• 沸点：
  116.5 °C(Press: 1 Torr)

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Chlor-bis-<3-fluor-phenyl>-phosphin 在 吡啶 、 silver tetrafluoroborate 、 水 作用下， 以 四氢呋喃 、 1,2-二氯乙烷 为溶剂， 反应 24.0h， 生成 ((3,5-di-tert-butyl-4-hydroxyphenyl)(phenyl)methyl)bis(3-fluorophenyl)phosphine oxide
  参考文献：
  名称：

  P(III)-亲核试剂银催化对醌甲基化物的区域选择性磷酸化

  摘要：

  P(III)-亲核试剂 (P(OR) 3 , ArP(OR) 2 , Ar 2 P-OR)银催化对醌甲基化物 ( p -QMs )区域选择性磷酸化的简单有效方法通过 Michaelis-Arbuzov 型反应建立。在温和条件下，广泛的 P(III)-亲核试剂和对-醌甲基化物具有良好的耐受性，从而得到预期的二芳基甲基取代的有机磷化合物，具有良好的产率。此外，以二烷基芳基亚膦酸酯(ArP(OR) 2 )为底物，可以得到一系列相应的对映异构体。对照实验和31还进行了 P NMR 跟踪实验以深入了解可能的反应机制。该协议可能对Michaelis-Arbuzov 型反应中 C( sp 3 )-P 键的形成具有重要意义。

  DOI：

  10.1021/acs.joc.1c01703

文献信息

• [EN] PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS<br/>[FR] COMPOSÉS DE PHOSPHINYLAMIDINE, COMPLEXES DE MÉTAL, SYSTÈMES DE CATALYSEUR, ET LEUR UTILISATION POUR OLIGOMÉRISER OU POLYMÉRISER DES OLÉFINES
  申请人：CHEVRON PHILLIPS CHEMICAL CO

  公开号：WO2011082192A1

  公开（公告）日：2011-07-07

  N2-phosphinyl amidine compounds, N2-phosphinyl amidinates, N2-phosphinyl amidine metal salt complexes, N2-phosphinyl amidinate metal salt complexes are described. Methods for making N2-phosphinyl amidine compounds, N2-phosphinyl amidinates, N2-phosphinyl amidine metal salt complexes, and N2-phosphinyl amidinate metal salt complexes are also disclosed. Catalyst systems utilizing the N2-phosphinyl amidine metal salt complexes and N2-phosphinyl amidinate metal salt complexes are also disclosed along with the use of the N2-phosphinyl amidine compounds, N2-phosphinyl amidinates, N2-phosphinyl amidine metal salt complexes, and N2-phosphinyl amidinate metal salt complexes for the oligomerization and/or polymerization of olefins.

  描述了N2-膦胺化合物、N2-膦胺酸盐、N2-膦胺金属盐络合物、N2-膦胺酸盐金属盐络合物。还公开了制备N2-膦胺化合物、N2-膦胺酸盐、N2-膦胺金属盐络合物和N2-膦胺酸盐金属盐络合物的方法。还公开了利用N2-膦胺金属盐络合物和N2-膦胺酸盐金属盐络合物的催化剂系统，以及利用N2-膦胺化合物、N2-膦胺酸盐、N2-膦胺金属盐络合物和N2-膦胺酸盐金属盐络合物进行烯烃的寡聚和/或聚合的用途。
• [EN] PHOSPHINYL FORMAMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS<br/>[FR] COMPOSÉS PHOSPHINYL FORMAMIDINE, COMPLEXES MÉTALLIQUES, SYSTÈMES DE CATALYSEUR, ET LEUR UTILISATION POUR OLIGOMÉRISER OU POLYMÉRISER DES OLÉFINES
  申请人：CHEVRON PHILLIPS CHEMICAL CO

  公开号：WO2015094207A1

  公开（公告）日：2015-06-25

  N2-phosphinyl formamidine compounds and N2-phosphinyl formamidine metal salt complexes are described. Methods for making N2-phosphinyl formamidine compounds and N2-phosphinyl formamidine metal salt complexes are also disclosed. Catalyst systems utilizing the N2-phosphinyl formamidine metal salt complexes are also disclosed along with the use of the N2-phosphinyl amidine compounds and N2- phosphinyl amidinate metal salt complexes for the oligomerization and/or polymerization of olefins.

  描述了N2-磷酰基甲酰胺化合物和N2-磷酰基甲酰胺金属盐配合物。还公开了制备N2-磷酰基甲酰胺化合物和N2-磷酰基甲酰胺金属盐配合物的方法。还公开了利用N2-磷酰基甲酰胺金属盐配合物的催化剂体系，以及利用N2-磷酰基胺化合物和N2-磷酰基胺金属盐配合物进行烯烃的寡聚和/或聚合的用途。
• Zn-Catalyzed Dehydroxylative Phosphorylation of Allylic Alcohols with P(III)-Nucleophiles
  作者：Biquan Xiong、Chonghao Shi、Yining Ren、Weifeng Xu、Yu Liu、Longzhi Zhu、Fan Cao、Ke-Wen Tang、Shuang-Feng Yin

  DOI：10.1021/acs.joc.3c02489

  日期：2024.3.1

  phosphinates, and phosphine oxides through the zinc-catalyzed dehydroxylative phosphorylation of allylic alcohols with P(III)-nucleophiles via a Michaelis–Arbuzov-type rearrangement is reported. A broad range of allylic alcohols and P(III)-nucleophiles (P(OR)3, ArP(OR)2, and Ar2P(OR)) are well tolerated in this reaction, and the expected dehydroxylative phosphorylation products could be synthesized with

  据报道，通过米氏-阿尔布佐夫型重排对烯丙醇与 P(III)-亲核试剂进行锌催化脱羟基磷酸化，合成二芳基烯丙基功能化膦酸酯、次膦酸酯和氧化膦的新颖且有效的方案。多种烯丙醇和 P(III)-亲核试剂（P(OR) 3 、ArP(OR) 2和 Ar 2 P(OR)）在此反应中具有良好的耐受性，并且可以合成预期的脱羟基磷酸化产物在最佳反应条件下具有良好至优异的产率。该反应可以很容易地扩大到克级合成水平。此外，通过逐步控制实验、动力学研究实验和31 P NMR跟踪实验，我们深入了解了该反应并提出了这种转变的可能机制。
• Process for the oligomerization of ethylene
  申请人：GULF RESEARCH & DEVELOPMENT COMPANY

  公开号：EP0046329A1

  公开（公告）日：1982-02-24

  Ethylene is oligomerized by contacting ethylene under oligomerization conditions with a nickel ylide defined by the following Formula I: wherein R1, R2, R3, R4, R5, R6, R7 and R8 are either alike or different members selected from the group consisting of hydrogen, alkyl radicals having from about one to about 24 carbon atoms, preferably from about one to about 10 carbon atoms; aryl radicals having from about six to about 20 carbon atoms, preferably from about six to about 10 carbon atoms; alkenyl radicals having from about two to about 30 carbons atoms, preferably from about two to about 20 carbon atoms; cycloalkyl radicals having from about three to about 40 carbon atoms, preferably from about three to about 30 carbon atoms; aralkyl and alkaryl radicals having from about six to about 40 carbon atoms, preferably from about six to about 30 carbon atoms; a halogen radical selected from the group consisting of fluorine, chlorine, bromine and iodine, preferably chlorine; a hydroxyl group; an alkoxy or aryloxy group; and a hydrocarbyl group, such as defined above, carrying halogen, hydroxyl or alkoxy or aryloxy; provided that at least one, preferably from about one to about four, of each of R1, to R8 is a sulfonato group (-SO3-) or an alkyl, aryl, alkenyl, cycloalkyl, aralkyl or alkaryl group carrying a sulfonato group; M is sulfur or oxygen, preferably oxygen; E is phosphorus, arsenic, antimony or nitrogen, preferably phosphorus; and F is phosphorus, arsenic or antimony, preferably phosphorus. This process is characterized by a relatively high reaction rate at low temperatures and pressures and results in the production of relatively high proportions of desirable trimer, tetramer, pentamer, and higher olefinic products.

  在低聚条件下，将乙烯与下式 I 所定义的镍酰亚胺接触，可使乙烯低聚： 其中 R1、R2、R3、R4、R5、R6、R7 和 R8 要么是相同的成员，要么是不同的成员，它们选自由氢、具有约 1 至约 24 个碳原子（最好是约 1 至约 10 个碳原子）的烷基、具有约 6 至约 20 个碳原子（最好是约 6 至约 10 个碳原子）的芳基组成的组；具有约 2 至约 30 个碳原子，最好是约 2 至约 20 个碳原子的烯基； 具有约 3 至约 40 个碳原子，最好是约 3 至约 30 个碳原子的环烷基； 具有约 6 至约 40 个碳原子，最好是约 6 至约 30 个碳原子的芳基和烷芳基；从氟、氯、溴和碘（最好是氯）组成的组中选出的卤素基；羟基；烷氧基或芳氧基；以及烃基，如上文所定义的，带有卤素、羟基或烷氧基或芳氧基的烃基；R1至R8中至少有一个，最好是约一个至约四个，是磺酸基（-SO3-）或带有磺酸基的烷基、芳基、烯基、环烷基、芳基或烷芳基；M是硫或氧，最好是氧；E是磷、砷、锑或氮，最好是磷；F是磷、砷或锑，最好是磷。该工艺的特点是在低温低压下反应速度相对较快，可生产出比例相对较高的理想三聚体、四聚体、五聚体和更高的烯烃产品。
• Nickel ylides
  申请人：GULF RESEARCH & DEVELOPMENT COMPANY

  公开号：EP0046331A2

  公开（公告）日：1982-02-24

  A new group of nickel ylides is provided that is highly active at relatively low operating temperatures and pressures in the oligomerization of ethylene. The compounds can be defined by the following Formula I: wherein R1, R2, R3, R4, R5, R6, R7 and R8 are either alike or different members selected from the group consisting of hydrogen, alkyl radicals having from about one to about 24 carbon atoms, preferably from about one to about 10 carbon atoms; aryl radicals having from about six to about 20 carbon atoms, preferably from about six to about 10 carbon atoms; alkenyl radicals having from about two to about 30 carbons atoms, preferably from about two to about 20 carbon atoms; cycloalkyl radicals having from about three to about 40 carbon atoms, preferably from about three to about 30 carbon atoms; aralkyl and alkaryl radicals having from about six to about 40 carbon atoms, preferably from about six to about 30 carbon atoms; a halogen radical selected from the group consisting of fluorine, chlorine, bromine and iodine, preferably chlorine; a hydroxyl group; an alkoxy or aryloxy group; and a hydrocarbyl group, such as defined above, carrying halogen, hydroxyl or alkoxy or aryloxy; provided that at least one, preferably from about one to about four, of each of R1 to R8 is a sulfonato group (-SO3-) or an alkyl, aryl, alkenyl, cycloalkyl, aralkyl or alkaryl group carrying a sulfonato group; M is sulfur or oxygen, preferably oxygen; E is phosphorus, arsenic, antimony or nitrogen, preferably phosphorus; and F is phosphorus, arsenic or antimony, preferably phosphorus.

  本研究提供了一组新的镍酰化物，在相对较低的工作温度和压力下，它们在乙烯的低聚过程中具有很高的活性。这些化合物可以用下式 I 来定义： 其中 R1、R2、R3、R4、R5、R6、R7 和 R8 要么是相同的成员，要么是不同的成员，它们选自氢、具有约 1 至约 24 个碳原子的烷基，最好是具有约 1 至约 10 个碳原子的烷基；具有约 6 至约 20 个碳原子的芳基，最好是具有约 6 至约 10 个碳原子的芳基；具有约 2 至约 30 个碳原子，最好是约 2 至约 20 个碳原子的烯基； 具有约 3 至约 40 个碳原子，最好是约 3 至约 30 个碳原子的环烷基； 具有约 6 至约 40 个碳原子，最好是约 6 至约 30 个碳原子的芳基和烷芳基；从氟、氯、溴和碘（最好是氯）组成的组中选出的卤素基；羟基；烷氧基或芳氧基；以及烃基，如上文所定义的，带有卤素、羟基或烷氧基或芳氧基的烃基；条件是 R1 至 R8 中至少有一个（最好是约一个至约四个）是磺酸基（-SO3-）或带有磺酸基的 烷基、芳基、烯基、环烷基、芳基或烷芳基；M 是硫或氧，最好是氧；E 是磷、砷、锑或氮，最好是磷；F 是磷、砷或锑，最好是磷。