2-isopropyl-4,7-dimethyloctahydro-2H-chromen-4-ol | 134869-70-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧杂环己烷
• 英文名称: 2-isopropyl-4,7-dimethyloctahydro-2H-chromen-4-ol
• CAS: 134869-70-8
• 化学式: C₁₄H₂₆O₂
• 分子量: 226.359
• InChiKey: GBVFPXPZZFAXDA-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  异蒲勒醇 、 异丁醛 在 silica gel 、 对甲苯磺酸 作用下， 以66%的产率得到2-isopropyl-4,7-dimethyloctahydro-2H-chromen-4-ol
  参考文献：
  名称：

  Solvent-free catalysed synthesis of tetrahydropyran odorants: the role of SiO

  摘要：

  An efficient, green and solvent-free catalysed Prins-cyclization reaction based on the simple grinding of an aldehyde and a homoallylic alcohol in the presence of catalytic amount of p-TSA on silica gel is reported. By this protocol were synthesized tetrahydropyran odorants including commercial Florol (R) and Clarycet (R), in one and two steps respectively.

  DOI：

  10.1590/s0103-50532010000800023