1-(Methylamino)cyclopentane-1-carboxamide | 1179878-43-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1-(Methylamino)cyclopentane-1-carboxamide
• CAS: 1179878-43-3
• 化学式: C₇H₁₄N₂O
• mdl: MFCD12151155
• 分子量: 142.2
• InChiKey: OESOTMQEPBMDID-UHFFFAOYSA-N

物化性质

• 沸点：
  301.3±21.0 °C(Predicted)
• 密度：
  1.05±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.857
• 拓扑面积：
  55.1
• 氢给体数：
  2
• 氢受体数：
  2

文献信息

• [EN] GLUCOSIDE DERIVATIVES AND USES THEREOF AS SGLT INHIBITORS<br/>[FR] DÉRIVÉS DE GLUCOSIDE ET UTILISATIONS DE CEUX-CI EN TANT QU'INHIBITEURS DE SGLT
  申请人：NOVARTIS AG

  公开号：WO2010031820A1

  公开（公告）日：2010-03-25

  The present invention relates to compounds of formula (I) and pharmaceutically acceptable salts, to formulations and uses in the treatment of metabolic disorders.

  本发明涉及化合物(I)及其药用盐，以及在治疗代谢性疾病中的配方和用途。
• PESTICIDAL COMPOSITIONS AND RELATED METHODS
  申请人：Dow AgroSciences LLC

  公开号：EP3071036A1

  公开（公告）日：2016-09-28
• Therapeutic agents and methods of use thereof for the modulation of angiogenesis
  申请人：Olson L. Gary

  公开号：US20070117758A1

  公开（公告）日：2007-05-24

  The present invention provides angiogenesis inhibitor compounds comprising a MetAP-2 inhibitory core coupled to a peptide, as well as pharmaceutical compositions comprising the angiogenesis inhibitor compounds and a pharmaceutically acceptable carrier. The present invention also provides methods of treating an angiogenic disease, e.g., cancer, in a subject by administering to the subject a therapeutically effective amount of one or more of the angiogenesis inhibitor compounds of the invention.
• Methods for treating bone associated diseases by the use of methionine aminopeptidase-2 inhibitors
  申请人：Hannig Gerhard

  公开号：US20070254843A1

  公开（公告）日：2007-11-01

  The instant invention provides methods and compositions for treating a subject suffering from bone associated diseases, such as osteoporosis.
• Methionine aminopeptidase-2 inhibitors and methods of use thereof
  申请人：Olson Gary L.

  公开号：US20090156624A1

  公开（公告）日：2009-06-18

  The present invention provides methods of parasitic infections, thymoma, and lymphoid malignancies in a subject by administering to the subject a therapeutically effective amount of one or more of the compounds of the invention.