1,4,5-tri-O-acetyl-1-deuterio-2,3,6-tri-O-methyl-D-galactitol | 64687-54-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,4,5-tri-O-acetyl-1-deuterio-2,3,6-tri-O-methyl-D-galactitol
• 英文别名: [(2S,3R,4S,5R)-4,5-diacetyloxy-1-deuterio-2,3,6-trimethoxyhexyl] acetate
• CAS: 64687-54-3
• 化学式: C₁₅H₂₆O₉
• 分子量: 351.358
• InChiKey: ATVQUEJOBOKGCC-KEAPVCGVSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  24
• 可旋转键数：
  14
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  107
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  Me D-Gul 生成 1,4,5-tri-O-acetyl-1-deuterio-2,3,6-tri-O-methyl-D-galactitol
  参考文献：
  名称：

  DOARES, STEVEN H.;ALBERSHEIM, PETER;DARVILL, ALAN G., CARBOHYDR. RES., 210,(1991) C. 311-317

  摘要：

  DOI：

文献信息

• Formation of Homooligosaccharides Using Base-Promoted Glycosylation of Unprotected Glycosyl Fluorides
  作者：Andreas Steinmann、Julian Thimm、Martin Matwiejuk、Joachim Thiem

  DOI：10.1021/ma100191d

  日期：2010.4.27

  Homooligomeric saccharides are of general interest with potential applications in chemical, pharmaceutical, and food industry as well as for materials with novel properties. This contribution describes a methodology of a base-promoted "single step self-oligomerization" of glycosyl fluorides as donors leading to oligomers with up to similar to 25 saccharide units. The influences of base and reaction time were examined. Linkage analysis of the corresponding alditol acetates by GC/MS allowed for calculation of average structural elements of oligomers.
• Characterization of the lipopolysaccharide O-antigen of Cronobacter turicensis HPB3287 as a polysaccharide containing a 5,7-diacetamido-3,5,7,9-tetradeoxy-d-glycero-d-galacto-non-2-ulosonic acid (legionaminic acid) residue
  作者：Leann L. MacLean、Evgeny Vinogradov、Franco Pagotto、Malcolm B. Perry

  DOI：10.1016/j.carres.2011.09.003

  日期：2011.11

  Cronobacter turicensis, previously known as Enterobacter sakazakii, is a Gram-negative opportunistic foodborne pathogen that has been reported as a cause of life-threatening neonatal infections. From chemical and physical analyses involving composition analysis, methylation, two-dimensional high-resolution nuclear magnetic resonance, and mass spectrometry methods, the antigenic 0-polysaccharide in the smooth-type lipopolysaccharide of C. turicensis (strain HPB 3287) was determined to be a high molecular mass polymer of a repeating pentasaccharide unit composed of D-galactose, D-glucose, 2-acetamido-2-deoxy-D-galactose, and 5,7-diacetamido-3,5,7,9-tetradeoxy-D-glycero-D-galacto-non-2-ulosonic acid (leg-ionaminic acid), in a molar ratio 2:1:1:1, and having the structure:alpha-D-Glcp1down arrow4[-> 3)-beta-D-Galp-(1 -> 3)-beta-D-GalpNAc-(1 -> 4)-alpha-D-Galp-(1 -> 4)-alpha-Leg5Ac7Ac-(2 ->](0). (C) 2011 Elsevier Ltd. All rights reserved.