4-[（1-氨基丙烷-2-基）氧基]甲苯 | 6440-97-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 4-[（1-氨基丙烷-2-基）氧基]甲苯
• 英文名称: 2-p-Tolyloxy-propylamine
• 英文别名: 2-(4-Methylphenoxy)propylamine；2-(4-methylphenoxy)propan-1-amine
• CAS: 6440-97-7
• 化学式: C₁₀H₁₅NO
• mdl: MFCD03840190
• 分子量: 165.235
• InChiKey: UFSYYRNCFQQPQC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  35.2
• 氢给体数：
  1
• 氢受体数：
  2

安全信息

• 危险等级：
  IRRITANT

文献信息

• Tetrasubstituted alkene compounds and their use
  申请人：Eisai R&D Management Co., Ltd.

  公开号：US10851065B2

  公开（公告）日：2020-12-01

  Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-α protein.

  本文公开了化合物或其药学上可接受的盐类，以及通过向需要治疗的对象施用治疗有效量的化合物或其药学上可接受的盐类来使用这些化合物治疗乳腺癌的方法。乳腺癌可以是ER阳性乳腺癌和/或需要治疗的受试者可以表达突变的ER-α蛋白。
• Amine polymer and preparation method and use thereof
  申请人：CHINA PETROLEUM & CHEMICAL CORPORATION

  公开号：US10968313B2

  公开（公告）日：2021-04-06

  The present invention relates to an amino polymer, its main chain is attached via a —O— group to a structure represented by the following formula (I). The present invention also relates to a process for producing said amino polymer and to its use as fuel oil detergent. Compared with the prior art, the fuel oil detergent of the present invention has the advantages such as a lower manufacturing cost and an improved deposit formation inhibition performance. In formula (I), groups and values are defined as described in the description.

  本发明涉及一种氨基聚合物，其主链通过-O-基团连接到下式（I）所代表的结构中。本发明还涉及生产所述氨基聚合物的工艺及其作为燃油清净剂的用途。与现有技术相比，本发明的燃油清净剂具有制造成本低、抑制沉积物形成性能更好等优点。 在式 (I) 中，基团和数值的定义如说明中所述。
• TETRASUBSTITUTED ALKENE COMPOUNDS AND THEIR USE
  申请人：Eisai R&D Management Co., Ltd.

  公开号：US20180127378A1

  公开（公告）日：2018-05-10

  Disclosed herein are compounds, or pharmaceutically acceptable salts thereof, and methods of using the compounds for treating breast cancer by administration to a subject in need thereof a therapeutically effective amount of the compounds or pharmaceutically acceptable salts thereof. The breast cancer may be an ER-positive breast cancer and/or the subject in need of treatment may express a mutant ER-α protein.