(5Z)-5-[[5-[4-(dimethylamino)phenyl]-1-methylpyrrol-2-yl]methylidene]-3-ethyl-1,3-oxazolidine-2,4-dithione | 1339921-27-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: (5Z)-5-[[5-[4-(dimethylamino)phenyl]-1-methylpyrrol-2-yl]methylidene]-3-ethyl-1,3-oxazolidine-2,4-dithione
• CAS: 1339921-27-5
• 化学式: C₁₉H₂₁N₃OS₂
• 分子量: 371.527
• InChiKey: RXURBJBBSGMYPN-ATVHPVEESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  25
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.26
• 拓扑面积：
  84.8
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• BROAD SPECTRUM ANTIVIRAL AND ANTIPARASITIC AGENTS
  申请人：The Regents of the University of California

  公开号：US20160207908A1

  公开（公告）日：2016-07-21

  The invention provides compounds represented by the formulae: (I) and (II) where the compounds are useful in treating, for example, viral and/or parasitic infections. Also provided are pharmaceutical compositions comprising the compounds and methods of treatment using the compounds.

  该发明提供了由公式（I）和（II）表示的化合物，这些化合物在治疗例如病毒性和/或寄生虫感染方面非常有用。还提供了包含这些化合物的药物组合物以及使用这些化合物的治疗方法。
• US9139575B2
  申请人：——

  公开号：US9139575B2

  公开（公告）日：2015-09-22
• [EN] BROAD SPECTRUM ANTIVIRAL AND ANTIPARASITIC AGENTS<br/>[FR] AGENTS ANTIVIRAUX ET ANTIPARASITAIRES À LARGE SPECTRE
  申请人：UNIV CALIFORNIA

  公开号：WO2011130419A2

  公开（公告）日：2011-10-20

  The invention provides compounds represented by the formulae: (I) and (II) where the compounds are useful in treating, for example, viral and/or parasitic infections. Also provided are pharmaceutical compositions comprising the compounds and methods of treatment using the compounds.