β-(N-benzyloxyamino)isovaleric acid methyl ester | 135765-51-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: β-(N-benzyloxyamino)isovaleric acid methyl ester
• 英文别名: Methyl 3-methyl-3-(phenylmethoxyamino)butanoate
• CAS: 135765-51-4
• 化学式: C₁₃H₁₉NO₃
• 分子量: 237.299
• InChiKey: FSSISSMIERSTSM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  17
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.46
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  β-(N-benzyloxyamino)isovaleric acid methyl ester 以100%的产率得到
  参考文献：
  名称：

  SHTAMBURG, V. G.;RUDCHENKO, V. F.;GRINEV, V. M.;DMITRENKO, A. A.;PLESHKOV+, IZV. AN CCCP. CEP. XIM.,(1991) N, S. 1069-1072

  摘要：

  DOI：
• 作为产物：
  描述：

  Methyl 3-[chloro(propan-2-yloxy)amino]-3-methylbutanoate 在 三乙胺 作用下， 反应 156.0h， 生成 β-(N-benzyloxyamino)isovaleric acid methyl ester
  参考文献：
  名称：

  Reactions of N-chloro-N-alkoxy-tert-alkylamines with isobutylene and methanol

  摘要：

  The addition of N-chloro-N-methoxy-tert-alkylamines to an olefin, which is assumed to proceed with the participation of alkoxynitrenium ions, was carried out for the first time. The methanolysis of N-chloro-N-alkoxy-tert-alkylamines in the presence of Et3N gives dialkoxyamines, and depending on the type of the N-alkyl substituent is accompanied by side reactions.

  DOI：

  10.1007/bf00961356

文献信息

• SHTAMBURG, V. G.;RUDCHENKO, V. F.;GRINEV, V. M.;DMITRENKO, A. A.;PLESHKOV+, IZV. AN CCCP. CEP. XIM.,(1991) N, S. 1069-1072
  作者：SHTAMBURG, V. G.、RUDCHENKO, V. F.、GRINEV, V. M.、DMITRENKO, A. A.、PLESHKOV+

  DOI：——

  日期：——
• Reactions of N-chloro-N-alkoxy-tert-alkylamines with isobutylene and methanol
  作者：V. G. Shtamburg、V. F. Rudchenko、V. M. Grinev、A. A. Dmitrenko、A. P. Pleshkova、R. G. Kostyanovskii

  DOI：10.1007/bf00961356

  日期：1991.5

  The addition of N-chloro-N-methoxy-tert-alkylamines to an olefin, which is assumed to proceed with the participation of alkoxynitrenium ions, was carried out for the first time. The methanolysis of N-chloro-N-alkoxy-tert-alkylamines in the presence of Et3N gives dialkoxyamines, and depending on the type of the N-alkyl substituent is accompanied by side reactions.