6-hexadecenioic acid | 28290-76-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-hexadecenioic acid
• 英文别名: Hexadec-6-ensaeure；trans-6-Hexadecensaeure；6(z)-hexadecenoic acid；cis-6hexadecenoic acid；hexadec-6-enoic acid；trans-6-Hexadecenoic acid；(E)-hexadec-6-enoic acid
• CAS: 28290-76-8
• 化学式: C₁₆H₃₀O₂
• 分子量: 254.413
• InChiKey: NNNVXFKZMRGJPM-ZHACJKMWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  18
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.81
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  6-hexadecenioic acid 在 甲酸 、 双氧水 作用下， 生成 6,7-dihydroxy-hexadecanoic acid
  参考文献：
  名称：

  Weitkamp; Smiljanic; Rothman, Journal of the American Chemical Society, 1947, vol. 69, p. 1938

  摘要：

  DOI：

文献信息

• METHOD FOR PRODUCING CARBOXYLIC ACID
  申请人：KON Yoshihiro

  公开号：US20100210873A1

  公开（公告）日：2010-08-19

  It is an object of this invention to provide a method for efficiently synthesizing monocarboxylic acid, dicarboxylic acid, and tricarboxylic acid with the use of unsaturated triacyl glycerol as a starting material and hydrogen peroxide as an oxidant. Such method comprises allowing unsaturated triacyl glycerol to react with hydrogen peroxide in the presence of a quaternary ammonium polybasic acid hydrogen salt and at least one member selected from the group consisting of tungstic acid, heterotungstic acid, and salts thereof.

  本发明的目的是提供一种利用不饱和三酰甘油作为起始物质和过氧化氢作为氧化剂高效合成单羧酸、二羧酸和三羧酸的方法。这种方法包括在季铵多元酸氢盐和从钨酸、异钨酸和其盐组成的群体中至少选择一种成员的存在下，允许不饱和三酰甘油与过氧化氢发生反应。
• [EN] FRAGRANCE COMPOSITION<br/>[FR] COMPOSITION POUR PARFUM
  申请人：KAO CORP

  公开号：WO2010082684A1

  公开（公告）日：2010-07-22

  A novel musk-based fragrance having an excellent musky fragrance is provided. Also provided is a fragrance composition containing, as an active ingredient, a macrocyclic lactone compound represented by the following formula (1): wherein A represents an ethylene group or an ethenylene group; and when A is an ethylene group, R represents an alkyl group having 3 carbon atoms, and n represents an integer from 1 to 6, while when A is an ethenylene group, R represents an alkyl group having 1 to 3 carbon atoms, and n represents an integer from 1 to 6.

  提供了一种具有优异麝香气味的新型麝香香料。还提供了一种香料组合物，其包含以下式（1）所表示的大环内酯化合物作为活性成分：其中，A代表乙烯基或乙烯基；当A是乙烯基时，R代表具有3个碳原子的烷基，n为1至6的整数，而当A为乙烯基时，R代表具有1至3个碳原子的烷基，n为1至6的整数。
• Process for the preparation of cis-6-hexadecenoic acid
  申请人：——

  公开号：US20020107412A1

  公开（公告）日：2002-08-08

  The invention relates to a process for the preparation of cis-6-hexadecenoic acid of the formula I, 1 which comprises reacting a 1 ) a triphenylphosphonium salt of the formula II, R 1 OOC—(CH 2 ) 5 -P(R 2 ) 3 +X − II with decanal of the formula III H 3 C—(CH 2 ) 8 —CH═O  III or a 2 ) a triphenylphosphonium salt of the formula IV, H 3 C—(CH 2 ) 9 -P(R 2 ) 3 +X − IV with an aldehyde of the formula V, R 1 OOC—(CH 2 ) 4 —CH═O  V in a Wittig reaction, and b) saponifying the ester, formed by process step a 1 ) or a 2 ), of the formula VI, 2 where the substituents R 1 , R 2 and X − have the meanings given in the description.

  本发明涉及一种制备式I的顺式-6-十六碳烯酸的方法，其中包括反应a1）式II的三苯基膦酸盐，R1OOC—（CH2）5-P（R2）3+X−II与式III的癸醛，H3C—（CH2）8—CH═O  III或a2）式IV的三苯基膦酸盐，H3C—（CH2）9-P（R2）3+X−IV与式V的醛，R1OOC—（CH2）4—CH═O  V在维特格反应中，以及b）皂化由过程步骤a1）或a2）形成的酯的式VI，其中取代基R1，R2和X−具有所述描述中给出的含义。
• Preparation of saccharide esters
  申请人：Scherl Franz-Xaver

  公开号：US20050019296A1

  公开（公告）日：2005-01-27

  A process for the preparation of saccharide esters by reacting saccharides with activated carboxylic acids in a dipolar-aprotic solvent and in the absence of a basic amine compound is described.

  本发明涉及一种通过在双极-无极溶剂中与活性羧酸反应制备糖苷酯的方法，且在无碱性胺类化合物存在的情况下进行。
• Novel liposome compositions
  申请人：Okada Kazushi

  公开号：US20060222696A1

  公开（公告）日：2006-10-05

  The present disclosure provides lipid-containing compositions, including targeted liposomes encapsulating drug, and pharmaceutical formulations thereof, as well as methods for the making and using the lipid-containing compositions, including the use of the targeted liposomes in the treatment of cancer and other diseases.

  本公开提供了含脂质的组合物，包括封装药物的靶向脂质体以及其制药配方，以及制备和使用含脂质的组合物的方法，包括使用靶向脂质体治疗癌症和其他疾病。