ethyl 3-ferrocenyl-1-methyl-1H-pyrazole-5-carboxylate | 1309044-69-6

• 英文名称: ethyl 3-ferrocenyl-1-methyl-1H-pyrazole-5-carboxylate
• CAS: 1309044-69-6
• 化学式: C₁₇H₁₈FeN₂O₂
• 分子量: 338.189
• InChiKey: LDOJYUPVFHJIIN-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  ethyl ester ferrocenoylpyruvic acid 、 甲基肼 以 溶剂黄146 为溶剂， 生成 ethyl 3-ferrocenyl-1-methyl-1H-pyrazole-5-carboxylate 、 ethyl 5-ferrocenyl-1-methyl-1H-pyrazole-3-carboxylate
  参考文献：
  名称：

  Synthesis and properties of 5-ferrocenyl-1H-pyrazole-3-carbaldehydes

  摘要：

  New ferrocene derivatives - ethyl esters of 1-aryl-5-ferrocenyl-1H-pyrazole-3-carboxylic acids were synthesized. The corresponding aldehydes were obtained from acid esters in two steps. The reductive amination reaction of 5-ferrocenyl-1-phenyl-1H-pyrazole-3-carbaldehyde was studied. Several of these compounds were investigated by cyclic voltammetry. All of them exhibited a reversible one-electron oxidation-reduction wave owing to the ferrocene-ferricinium redox couple with a positive shift (0.51-0.69 V) compared with that of ferrocene (0.46 V). The X-ray crystal structure of the ethyl ether 1-(3-chloro-2-fluorophenyl)-5-ferrocenyl-1H-pyrazole-3-carboxylic acid is also presented. (C) 2010 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2010.11.018