m-Methoxiphenyl Ethansulfonat | 59970-39-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: m-Methoxiphenyl Ethansulfonat
• CAS: 59970-39-7
• 化学式: C₉H₁₂O₄S
• 分子量: 216.258
• InChiKey: WQPSYXLCJZNIIT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.42
• 重原子数：
  14.0
• 可旋转键数：
  4.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  52.6
• 氢给体数：
  0.0
• 氢受体数：
  4.0

反应信息

• 作为产物：
  描述：

  3-甲氧基苯酚 、 乙基磺酰氯 在 吡啶 作用下， 生成 m-Methoxiphenyl Ethansulfonat
  参考文献：
  名称：

  On the mechanism of cleavage of aryl alkanesulfonates by electron donors

  摘要：

  DOI：

  10.1021/ja00425a022

文献信息

• Synthesis, anti-oomycete activity, and SAR studies of paeonol derivatives
  作者：Yue-E Tian、Di Sun、Xiao-Xiao Han、Jin-Ming Yang、Song Zhang、Nan-Nan Feng、Li-Na Zhu、Zhong-Yuan Xu、Zhi-Ping Che、Sheng-Ming Liu、Xiao-Min Lin、Jia Jiang、Gen-Qiang Chen

  DOI：10.1080/10286020.2020.1718116

  日期：2021.2.1

  Three series of sulfonate derivatives of paeonol were synthesized and screened in vitro for their anti-oomycete activity against P. capsici, respectively. Among all the compounds, 4m displayed the best promising and pronounced anti-oomycete activity against P. capsici than zoxamide, with the EC50 values of 24.51 and 26.87 mg/L, respectively. The results show that acetyl and 4-OCH3 are two necessary groups. The existence of these two sites is closely related to the anti-oomycete activity. Relatively speaking, hydroxyl group is well tolerated, and the results showed that after modification of hydroxyl group with sulfonyl, the anti-oomycete activity was significantly increased.[GRAPHICS].