O,O'-diphenyl-1-amino-2-furylmethylphosphonate | 169334-93-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: O,O'-diphenyl-1-amino-2-furylmethylphosphonate
• 英文别名: Diphenoxyphosphoryl(furan-2-yl)methanamine
• CAS: 169334-93-4
• 化学式: C₁₇H₁₆NO₄P
• 分子量: 329.292
• InChiKey: HFVAFNOMSAQAFJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  23
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  74.7
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  O,O'-diphenyl-1-amino-2-furylmethylphosphonate 在 三乙胺 作用下， 以 氯仿 、 丙酮 为溶剂， 反应 2.0h， 生成 O,O-diphenyl [furan-2-yl-(2-selenomorpholin-4-yl-acetylamino)methyl] phosphonate
  参考文献：
  名称：

  SYNTHESIS OF O,O-DIPHENYL [SUBSTITUTED (2-SELENOMORPHOLIN-4-YL-ACETYL AMINO)] ALKYL PHOSPHONATES

  摘要：

  A series of O,O-diphenyl [substituted (2-selenomorpholin-4-yl-acetyl amino)] alkyl phosphonates were synthesized by the reactions of selenomorpholine with O,O-diphenyl 2-chloro- acetylamino alkyl phosphonates. The structures of all new compounds have been confirmed by H-1 NMR, P-31 NMR, IR spectroscopy, Mass spectroscopy and elemental analyses.

  DOI：

  10.1080/10426500490459687
• 作为产物：
  描述：

  N-benzyl-1-(furan-2-yl)methanimine 在 palladium on activated charcoal 氢气 作用下， 以 盐酸 、 甲醇 、 氯仿 、 甲苯 为溶剂， 反应 4.0h， 生成 O,O'-diphenyl-1-amino-2-furylmethylphosphonate
  参考文献：
  名称：

  Boduszek, Bogdan, Phosphorus, Sulfur and Silicon and the Related Elements, 1995, vol. 104, # 14, p. 63 - 70

  摘要：

  DOI：

文献信息

• Synthesis and Biological Activity of Heterocyclic Aminophosphonates
  作者：Bogdan Boduszek

  DOI：10.1080/10426509908546274

  日期：1999.1.1

  aminometh-anephosphonic acid and also phosphonic analogues of proline and homoproline. The obtained heterocyclic aminophosphonates were used as starting materials for synthesis of some peptidyl phosphonates. The compounds were evaluated as inhibitors of serine proteases. Most of the obtained heterocyclic aminophosphonates were preliminary tested as potential herbicides against selected plants, and some of them showed

  介绍了多种制备杂环氨基膦酸酯的合成方法；它们是关于氨基甲烷膦酸的呋喃基、噻吩基、吡咯基和吡啶基衍生物以及脯氨酸和高脯氨酸的膦酸类似物。得到的杂环氨基膦酸酯被用作合成一些肽基膦酸酯的原料。这些化合物被评估为丝氨酸蛋白酶抑制剂。大部分获得的杂环氨基膦酸盐作为对选定植物的潜在除草剂进行了初步测试，其中一些显示了除草活性。
• SYNTHESIS OF O,O-DIPHENYL [SUBSTITUTED (2-SELENOMORPHOLIN-4-YL-ACETYL AMINO)] ALKYL PHOSPHONATES
  作者：Liming Hu、Zhiyuan Chen、Shengmei Lu、Xueshu Li、Zhaojie Liu、Hansheng Xu

  DOI：10.1080/10426500490459687

  日期：2004.6

  A series of O,O-diphenyl [substituted (2-selenomorpholin-4-yl-acetyl amino)] alkyl phosphonates were synthesized by the reactions of selenomorpholine with O,O-diphenyl 2-chloro- acetylamino alkyl phosphonates. The structures of all new compounds have been confirmed by H-1 NMR, P-31 NMR, IR spectroscopy, Mass spectroscopy and elemental analyses.
• Boduszek, Bogdan, Phosphorus, Sulfur and Silicon and the Related Elements, 1995, vol. 104, # 14, p. 63 - 70
  作者：Boduszek, Bogdan

  DOI：——

  日期：——