| 1417170-17-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 1417170-17-2
• 化学式: C₂₀H₃₄N₂O₁₀
• 分子量: 462.497
• InChiKey: DANRJRSSIVWQBO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.02
• 重原子数：
  32.0
• 可旋转键数：
  16.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  168.77
• 氢给体数：
  3.0
• 氢受体数：
  9.0

反应信息

• 作为反应物：
  描述：

  在 苯甲醚 、 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以91%的产率得到N-(3-aminopropyl) diethano succinate amine
  参考文献：
  名称：

  Synthesis and properties of new water-soluble aliphatic hyperbranched poly(amido acids) with high pH-dependent photoluminescence

  摘要：

  Water-soluble fluorescent hyperbranched poly(amido acids) (HBPAAs), based on wholly aliphatic structures were prepared through direct self-condensation of N-(3-aminopropyl) diethano succinate amine (APDESA, AB(2) monomer) in the presence of N,N-dicyclohexylcarbodiimide (DCC) as a condensation agent. The resulting HBPAAs were soluble in water, DMF and THF, and the structure of synthesized AB(2) monomer and polymers was confirmed by IR, H-1, and C-13 NMR measurements. TEM image indicated that the HBPAAs self-assembled in H2O to form a spherical micelle with a diameter ranging from 30 to 50 nm. A significant pH-dependent profile of fluorescent intensity in the pH range from 3 to 10 was observed, wherein pH 4 provided a critical jump as the solution pH was increased. Further increasing the pH to 10 decreased the fluorescence because of partial hydrolysis. Strong fluorescence emission was observed at 395 nm in aqueous media and the fluorescence quantum yields are to 23%. These amphiphilic HBPAAs, with excellent water-solubility, void-rich space, multiple functional peripheries and high blue fluorescence, have potential uses as tracing nanocarriers and molecular-level containers. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2012.12.013
• 作为产物：
  描述：

  丁二酸酐 、 Boc-N-(3-aminopropyl)diethanolamine carbonate 在 吡啶 、 4-二甲氨基吡啶 作用下， 以 二氯甲烷 为溶剂， 反应 24.0h， 以95%的产率得到
  参考文献：
  名称：

  Synthesis and properties of new water-soluble aliphatic hyperbranched poly(amido acids) with high pH-dependent photoluminescence

  摘要：

  Water-soluble fluorescent hyperbranched poly(amido acids) (HBPAAs), based on wholly aliphatic structures were prepared through direct self-condensation of N-(3-aminopropyl) diethano succinate amine (APDESA, AB(2) monomer) in the presence of N,N-dicyclohexylcarbodiimide (DCC) as a condensation agent. The resulting HBPAAs were soluble in water, DMF and THF, and the structure of synthesized AB(2) monomer and polymers was confirmed by IR, H-1, and C-13 NMR measurements. TEM image indicated that the HBPAAs self-assembled in H2O to form a spherical micelle with a diameter ranging from 30 to 50 nm. A significant pH-dependent profile of fluorescent intensity in the pH range from 3 to 10 was observed, wherein pH 4 provided a critical jump as the solution pH was increased. Further increasing the pH to 10 decreased the fluorescence because of partial hydrolysis. Strong fluorescence emission was observed at 395 nm in aqueous media and the fluorescence quantum yields are to 23%. These amphiphilic HBPAAs, with excellent water-solubility, void-rich space, multiple functional peripheries and high blue fluorescence, have potential uses as tracing nanocarriers and molecular-level containers. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.polymer.2012.12.013