4,7-Octadiin-1-ol | 34456-16-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4,7-Octadiin-1-ol
• 英文别名: octa-4,7-diyn-1-ol
• CAS: 34456-16-1
• 化学式: C₈H₁₀O
• 分子量: 122.167
• InChiKey: DBTDAXLOGXXYPZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  9
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS<br/>[FR] SYNTHÈSE ET UTILISATION D'ACIDES GRAS POLYINSATURÉS OMÉGA-HYDROXYLÉS
  申请人：UNIV CALIFORNIA

  公开号：WO2018035208A1

  公开（公告）日：2018-02-22

  The present invention provides a synthetic chemical method for preparing ω-hydroxylated polyunsaturated fatty acids (PUFAs) including 20-hydroxyeicosatetraenoic acid (20-HETE), 20-hydroxyeicosapentaenoic acid (20-HEPE), and 22-hydroxydocosahexaenoic acid (22-HDoHE) and a method of use thereof for treating cancer and macular degeneration.

  本发明提供了一种合成化学方法，用于制备包括20-羟基二十碳四烯酸（20-HETE）、20-羟基二十碳五烯酸（20-HEPE）和22-羟基二十二碳六烯酸（22-HDoHE）在内的ω-羟基多不饱和脂肪酸（PUFAs），以及用于治疗癌症和黄斑变性的使用方法。
• Synthesis and use of omega-hydroxylated polyunsaturated fatty acids
  申请人：THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US10689595B2

  公开（公告）日：2020-06-23

  The present invention provides a synthetic chemical method for preparing ω-hydroxylated polyunsaturated fatty acids (PUFAs) including 20-hydroxyeicosatetraenoic acid (20-HETE), 20-hydroxyeicosapentaenoic acid (20-HEPE), and 22-hydroxydocosahexaenoic acid (22-HDoHE) and a method of use thereof for treating cancer and macular degeneration.

  本发明提供了一种制备ω-羟基多不饱和脂肪酸（PUFAs）（包括 20-羟基二十碳四烯酸（20-HETE）、20-羟基二十碳五烯酸（20-HEPE）和 22-羟基二十二碳六烯酸（22-HDoHE））的化学合成方法及其用于治疗癌症和黄斑变性的方法。
• Synthesis and use of ω-hydroxylated polyunsaturated fatty acids
  申请人：THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US11001783B2

  公开（公告）日：2021-05-11

  The present invention provides a synthetic chemical method for preparing ω-hydroxylated polyunsaturated fatty acids (PUFAs) including 20-hydroxyeicosatetraenoic acid (20-HETE), 20-hydroxyeicosapentaenoic acid (20-HEPE), and 22-hydroxydocosahexaenoic acid (22-HDoHE) and a method of use thereof for treating cancer and macular degeneration.

  本发明提供了一种制备ω-羟基多不饱和脂肪酸（PUFAs）（包括 20-羟基二十碳四烯酸（20-HETE）、20-羟基二十碳五烯酸（20-HEPE）和 22-羟基二十二碳六烯酸（22-HDoHE））的化学合成方法及其用于治疗癌症和黄斑变性的方法。
• SYNTHESIS AND USE OF OMEGA-HYDROXYLATED POLYUNSATURATED FATTY ACIDS
  申请人：THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

  公开号：US20190270950A1

  公开（公告）日：2019-09-05

  The present invention provides a synthetic chemical method for preparing ω-hydroxylated polyunsaturated fatty acids (PUFAs) including 20-hydroxyeicosatetraenoic acid (20-HETE), 20-hydroxyeicosapentaenoic acid (20-HEPE), and 22-hydroxydocosahexaenoic acid (22-HDoHE) and a method of use thereof for treating cancer and macular degeneration.