tert-butyl N-[(tert-butoxy)carbonyl]-N-(3-hydroxypropyl)carbamate | 1824163-90-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: tert-butyl N-[(tert-butoxy)carbonyl]-N-(3-hydroxypropyl)carbamate
• 英文别名: tert-butyl N-(3-hydroxypropyl)-N-[(2-methylpropan-2-yl)oxycarbonyl]carbamate
• CAS: 1824163-90-7
• 化学式: C₁₃H₂₅NO₅
• 分子量: 275.34
• InChiKey: OHUHJOQGBBBLLU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  19
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  76.1
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Method for producing polyalkylene glycol derivative having amino group at end, polymerization initiator for use in the same, and alcohol compound as raw material for the polymerization initiator
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：US10472377B2

  公开（公告）日：2019-11-12

  A method for producing a narrowly distributed and high-purity polyalkylene glycol derivative having an amino group at an end, a polymerization initiator for use in the method, and a precursor of the polymerization initiator are provided. The present invention provides: a method for producing a polyalkylene glycol derivative having an amino group at an end, using, as a polymerization initiator, a compound represented by the general formula (I); a compound represented by the following general formula (I); and a precursor thereof: wherein RA1a and RA1b each independently represent a protective group of the amino group, or one of RA1a and RA1b represents H and the other represents a protective group of the amino group, or RA1a and RA1b bind to each other to represent a cyclic protective group forming a ring; RA2 represents a linear, branched, or cyclic hydrocarbon group having 1 to 6 carbon atoms; RA3 represents a single bond, or a linear, branched, or cyclic hydrocarbon group having 1 to 20 carbon atoms, and the hydrocarbon group may contain a heteroatom; the total number of carbon atoms (or the total number of carbon atoms and heteroatoms) of RA2 and RA3 is 4 or more; and M represents an alkali metal.

  本发明提供了一种生产末端具有氨基的窄分布高纯度聚亚烷基二醇衍生物的方法、一种用于该方法的聚合引发剂以及一种聚合引发剂的前体。 本发明提供了：一种生产末端具有氨基的聚亚烷基二醇衍生物的方法，该方法使用通式（I）所代表的化合物作为聚合引发剂；一种由以下通式（I）所代表的化合物；以及其前体： 其中 RA1a 和 RA1b 各自独立地代表氨基的保护基团，或 RA1a 和 RA1b 中的一个代表 H，另一个代表氨基的保护基团，或 RA1a 和 RA1b 相互结合代表形成环的环状保护基团；RA2 代表具有 1 至 6 个碳原子的线性、支链或环状烃基；RA3 代表单键，或具有 1 至 20 个碳原子的线性、支链或环状烃基，且该烃基可能含有一个杂原子；RA2 和 RA3 的碳原子总数（或碳原子和杂原子总数）为 4 或更多；以及 M 代表碱金属。
• METHOD FOR PRODUCING POLYALKYLENE GLYCOL DERIVATIVE HAVING AMINO GROUP AT END, POLYMERIZATION INITIATOR FOR USE IN THE SAME, AND ALCOHOL COMPOUND AS RAW MATERIAL FOR THE POLYMERIZATION INITIATOR
  申请人：Shin-Etsu Chemical Co., Ltd.

  公开号：EP3053944B1

  公开（公告）日：2021-10-06
• Isoindoline Derivatives For The Treatment Of Arrhythmias
  申请人：Bjore Annika

  公开号：US20100298392A1

  公开（公告）日：2010-11-25

  There is provided compounds of formula I, wherein R 1 to R 7 have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.
• US9708350B2
  申请人：——

  公开号：US9708350B2

  公开（公告）日：2017-07-18