(2,5-dioxopyrrolidin-1-yl) 2-(5,7-difluoro-6-hydroxy-1,3-benzothiazol-2-yl)-4-methyl-5H-1,3-thiazole-4-carboxylate | 1260754-18-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (2,5-dioxopyrrolidin-1-yl) 2-(5,7-difluoro-6-hydroxy-1,3-benzothiazol-2-yl)-4-methyl-5H-1,3-thiazole-4-carboxylate
• CAS: 1260754-18-4
• 化学式: C₁₆H₁₁F₂N₃O₅S₂
• 分子量: 427.409
• InChiKey: HLOXSANRMCYMIB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  28
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.31
• 拓扑面积：
  163
• 氢给体数：
  1
• 氢受体数：
  11

文献信息

• [EN] NOVEL FLUORESCENT DYES AND USES THEREOF<br/>[FR] NOUVEAUX COLORANTS FLUORESCENTS ET LEURS UTILISATIONS
  申请人：BECKMAN COULTER INC

  公开号：WO2011008912A1

  公开（公告）日：2011-01-20

  The present invention provides fluorescent dyes that are based on firefly luciferin structure. These dyes are optimally excited at shorter wavelengths and have Stokes shift of at least 50 nm. The fluorescent dyes of the invention are useful for preparation of dye-conjugates, which can be used in detection of an analyte in a sample.

  本发明提供基于萤火虫荧光素结构的荧光染料。这些染料在较短波长下被最佳激发，并具有至少50纳米的斯托克斯位移。本发明的荧光染料可用于制备染料偶联物，该偶联物可用于检测样品中的分析物。
• Novel Fluorescent Dyes and Uses Thereof
  申请人：AKHAVAN-TAFTI Hashem

  公开号：US20110014599A1

  公开（公告）日：2011-01-20

  The present invention provides fluorescent dyes that are based on firefly luciferin structure. These dyes are optimally excited at shorter wavelengths and have Stokes shift of at least 50 nm. The fluorescent dyes of the invention are useful for preparation of dye-conjugates, which can be used in detection of an analyte in a sample.

  本发明提供了基于萤火虫荧光素结构的荧光染料。这些染料在较短波长下受到最佳激发，并且至少具有50纳米的斯托克斯位移。本发明的荧光染料可用于制备染料共轭物，可用于样本中分析物的检测。
• FLUORESCENT DYES AND USES THEREOF
  申请人：Beckman Coulter, Inc.

  公开号：EP2454329B1

  公开（公告）日：2018-04-18
• POLYMERIC DYES HAVING A BACKBONE COMPRISING ORGANOPHOSPHATE UNITS
  申请人：SONY CORPORATION

  公开号：US20210285953A1

  公开（公告）日：2021-09-16

  Compounds useful as fluorescent or colored dyes are disclosed. The compounds have the structure (I) or a stereoisomer, tautomer or salt thereof, wherein R 1 , R 2 , R 3 , R 4 , R 5 , L 1a , L 1b , L 2 , L 3 , L 4 , L 5 , L 6 , L 7 , M 1 , M 2 , q, w, m and n are as defined herein. Methods associated with preparation and use of such compounds are also provided.
• US8367842B2
  申请人：——

  公开号：US8367842B2

  公开（公告）日：2013-02-05