2-(2-{2-[2-(1-hydroxyethyl-undecyloxy)-ethoxy]-ethoxy}-ethoxy)dodecan-1-ol | 235091-03-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-(2-{2-[2-(1-hydroxyethyl-undecyloxy)-ethoxy]-ethoxy}-ethoxy)dodecan-1-ol
• CAS: 235091-03-9
• 化学式: C₃₀H₆₂O₆
• 分子量: 518.819
• InChiKey: UDOFXDAOBZMPTO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.84
• 重原子数：
  36.0
• 可旋转键数：
  31.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  77.38
• 氢给体数：
  2.0
• 氢受体数：
  6.0

反应信息

• 作为反应物：
  描述：

  2-(2-{2-[2-(1-hydroxyethyl-undecyloxy)-ethoxy]-ethoxy}-ethoxy)dodecan-1-ol 在 六甲基磷酰三胺 、 硫酸 、 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 反应 40.0h， 生成 [2-(2-{2-[2-(1-methoxycarbonylmethoxymethylundecyloxy)-ethoxy]-ethoxy}-ethoxy)dodecyloxy]acetic acid methyl ester
  参考文献：
  名称：

  Synthesis and surface-active properties of a series of new anionic gemini compounds

  摘要：

  The synthesis of a series of new anionic dimeric amphiphiles 1-5 is described. The CMC and both static and dynamic surface tensions have been measured using the Wilhelmy plate technique and the maximum bubble pressure method. Results are compared to those obtained with the corresponding monomeric surfactants and relevant monomeric or dimeric compounds described in the literature. The relationship between the structural features of the different compounds and their properties is discussed. In particular an increase in the length of the connecting group between the two lipophilic chains lowers the CMC of the compounds which is different from results reported in the literature for other gemini compounds. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

  DOI：

  10.1016/s0009-3084(99)00003-1
• 作为产物：
  描述：

  1-benzyloxy-2-(2-{2-[2-(1-benzyloxyethyl-undecyloxy)-ethoxy]-ethoxy}-ethoxy)dodecane 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 以99%的产率得到2-(2-{2-[2-(1-hydroxyethyl-undecyloxy)-ethoxy]-ethoxy}-ethoxy)dodecan-1-ol
  参考文献：
  名称：

  Synthesis and surface-active properties of a series of new anionic gemini compounds

  摘要：

  The synthesis of a series of new anionic dimeric amphiphiles 1-5 is described. The CMC and both static and dynamic surface tensions have been measured using the Wilhelmy plate technique and the maximum bubble pressure method. Results are compared to those obtained with the corresponding monomeric surfactants and relevant monomeric or dimeric compounds described in the literature. The relationship between the structural features of the different compounds and their properties is discussed. In particular an increase in the length of the connecting group between the two lipophilic chains lowers the CMC of the compounds which is different from results reported in the literature for other gemini compounds. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

  DOI：

  10.1016/s0009-3084(99)00003-1