S-dodecyl-S'-(α,α-dimethylpentafluorophenyl acetate)trithiocarbonate | 1174764-26-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚酯
• 英文名称: S-dodecyl-S'-(α,α-dimethylpentafluorophenyl acetate)trithiocarbonate
• 英文别名: 2-(Dodecylthiocarbonothioylthio)-2-methylpropionic acid pentafluorophenyl ester；(2,3,4,5,6-pentafluorophenyl) 2-dodecylsulfanylcarbothioylsulfanyl-2-methylpropanoate
• CAS: 1174764-26-1
• 化学式: C₂₃H₃₁F₅O₂S₃
• 分子量: 530.688
• InChiKey: XBUCQRRMAZYXHN-UHFFFAOYSA-N

物化性质

• 沸点：
  555.3±50.0 °C(Predicted)
• 密度：
  1.203 g/mL at 25 °C
• 闪点：
  >110℃

计算性质

• 辛醇/水分配系数(LogP)：
  10.4
• 重原子数：
  33
• 可旋转键数：
  17
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  109
• 氢给体数：
  0
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  1,2-二棕榈酰-外消旋-甘油-3-磷酰乙醇胺 、 S-dodecyl-S'-(α,α-dimethylpentafluorophenyl acetate)trithiocarbonate 在 N,N-二异丙基乙胺 作用下， 以 甲醇 、 氯仿 为溶剂， 反应 5.0h， 以71%的产率得到
  参考文献：
  名称：

  Control of the Molecular Orientation of Membrane-Anchored Biomimetic Glycopolymers

  摘要：

  Quantifying and controlling the orientation of surface-bound macromolecules is crucial to a wide range of processes in areas as diverse as biology, materials science, and nanotechnology. Methods capable of directing orientation, as well as an understanding of the underlying physical mechanisms are, however, lacking. In this paper, we describe experiments in which the conformations of structurally well-defined polymers anchored to fluid lipid membranes were probed using Fluorescence Interference Contrast Microscopy (FLIC), an optical technique that provides topographic information with few-nanometer precision. The novel rodlike polymers mimic the architecture of mucin glycoproteins and feature a phospholipid tail for membrane incorporation and a fluorescent optical probe for FLIC imaging situated at the opposite termini of the densely glycosylated polymeric backbones. We find that the orientation of the rigid, approximately 30 nm long glycopolymers depends profoundly on the properties of the optical reporter. Molecules terminated with Alexa Fluor 488 projected away from the lipid bilayer by 11 +/- 1 nm, consistent with entropy-dominated sampling of the membrane-proximal space. Molecules terminated with Texas Red lie flat at the membrane (height, 0 +/- 2 nm), implying that interactions between Texas Red and the bilayer dominate the polymers' free energy. These results demonstrate the design of macromolecules with specific orientational preferences, as well as nanometer-scale measurement of their orientation. Importantly, they reveal that seemingly minute changes in molecular structure, in this case fluorophores that comprise only 2% of the total molecular weight, can significantly alter the molecule's presentation to the surrounding environment.

  DOI：

  10.1021/ja903114g
• 作为产物：
  描述：

  三氟乙酸五氟苯酯 、 2-[十二烷硫基(硫代羰基)硫基]-2-甲基丙酸 在 N,N-二异丙基乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 1.0h， 以95%的产率得到S-dodecyl-S'-(α,α-dimethylpentafluorophenyl acetate)trithiocarbonate
  参考文献：
  名称：

  用于微阵列应用的双末端功能化粘蛋白样糖聚合物的合成和微接触印刷

  摘要：

  点击查看：糖聚合物可用于在类似天然结构的微阵列上展示聚糖。在铜催化剂存在下，通过微接触印刷将结构均匀的炔烃封端的粘蛋白模拟糖聚合物（见图；TR=荧光团）印刷在叠氮化物功能化的芯片上。表面结合的糖聚合物以配体特异性方式结合凝集素。

  DOI：

  10.1002/anie.200805756

文献信息

• Polymerizable sulfonamide compounds and polymers thereof
  申请人：Massachusetts Institute of Technology

  公开号：US11155674B2

  公开（公告）日：2021-10-26

  Methods, compositions, reagents, and systems that allow for the preparation and utilization of sulfonamide salt polymer electrolytes are disclosed herein. Methods and reagents to prepare sulfonamide salt monomers are also disclosed herein. The sulfonamide salt polymer electrolytes can be used as components in energy storage devices, conductive materials, electrochemical cells, gels, adhesives, and drug delivery vehicles.

  本文公开了允许制备和利用磺胺盐聚合物电解质的方法、组合物、试剂和系统。本文还公开了制备磺胺盐单体的方法和试剂。磺胺盐聚合物电解质可用作能量存储设备、导电材料、电化学电池、凝胶、粘合剂和药物输送载体中的组件。
• PROTEIN AGGREGATION INHIBITOR
  申请人：Osaka Organic Chemical Industry Ltd.

  公开号：EP3296314A1

  公开（公告）日：2018-03-21

  Provided is a protein aggregation inhibitor capable of inhibiting aggregation of a protein even when the protein is heated, and further, capable of inhibiting a decrease in the protein activity even when the protein is heated, which characteristically contains a sulfobetaine polymer obtained by polymerizing monomer components containing sulfobetaine monomer represented by the formula (I): wherein R1 is a hydrogen atom or a methyl group, R2 is an alkylene group having a carbon number of 1 - 4, R3 is an alkyl group having a carbon number of 1 - 4, R4 is an alkylene group having a carbon number of 1 - 4, and X is an -NH- group or an - O- group.

  本发明提供了一种蛋白质聚集抑制剂，即使在加热蛋白质的情况下也能抑制蛋白质的聚集，而且即使在加热蛋白质的情况下也能抑制蛋白质活性的降低，其特征在于含有一种磺基甜菜碱聚合物，该聚合物是通过聚合含有由式（I）表示的磺基甜菜碱单体的单体成分而获得的： 其中 R1 是氢原子或甲基，R2 是碳原子数为 1-4 的亚烷基，R3 是碳原子数为 1-4 的烷基，R4 是碳原子数为 1-4 的亚烷基，X 是-NH-基团或-O-基团。
• GEL MATERIAL
  申请人：National University Corporation Hokkaido University

  公开号：EP3828225A1

  公开（公告）日：2021-06-02

  Disclosed is a gel material having a high water content and excellent mechanical properties. The gel material includes repeating units derived from the following monomers (A) and (B): (A) an anionic monomer containing a polymerizable carbon-carbon multiple bond and an aromatic ring, and (B) a cationic monomer containing a polymerizable carbon-carbon multiple bond and an aromatic ring. The gel material has a water content of 20% by mass to 95% by mass, a tensile elastic modulus of 9 MPa to 1000 MPa, and a tensile elongation at break of 50% to 5000%.

  本发明公开了一种具有高含水量和优异机械性能的凝胶材料。该凝胶材料包括由以下单体（A）和（B）衍生的重复单元：（A）含有可聚合碳-碳多键和芳香环的阴离子单体，以及（B）含有可聚合碳-碳多键和芳香环的阳离子单体。凝胶材料的含水量为 20% 至 95%，拉伸弹性模量为 9 兆帕至 1000 兆帕，拉伸断裂伸长率为 50% 至 5000%。
• Cross-linked impact modified polyphosphazenes
  申请人：INTERNATIONAL BUSINESS MACHINES CORPORATION

  公开号：US11059960B2

  公开（公告）日：2021-07-13

  A flame retardant composition and a method of making a flame retardant composition is provided. In an embodiment, the method includes reacting a phosphazene material with an acrylamide monomer material to form a functionalized phosphazene material; initiating a polymerization reaction on a reaction mixture comprising a functionalized phosphazene material and one or more monomers to form a first impact-modified phosphazene material; and reacting the first impact-modified phosphazene material with a poly(dichlorophosphazene) monomer material, and a reactant selected from the group consisting of R1OH, HNR2R3, or a combination thereof, to form a second impact-modified phosphazene material.

  本发明提供了一种阻燃组合物和一种阻燃组合物的制造方法。在一个实施方案中，该方法包括将磷化烯材料与丙烯酰胺单体材料反应，形成官能化磷化烯材料；在包含官能化磷化烯材料和一种或多种单体的反应混合物上引发聚合反应，形成第一抗冲改性磷化烯材料；将第一抗冲改性磷苯材料与聚（二氯磷苯）单体材料和选自 R1OH、HNR2R3 或其组合的反应物反应，形成第二抗冲改性磷苯材料。
• Polymers and uses thereof
  申请人：Massachusetts Institute of Technology

  公开号：US11034788B2

  公开（公告）日：2021-06-15

  The present invention provides polymers and methods of preparing the same. In certain embodiments, the polymers comprise acrylate repeating units that have been derivatized (e.g., reduced and/or substituted) to form new polymeric structures. In certain embodiments, the polymers described herein self-assemble to form well-defined nanostructures. In some instances, the nanostructures exhibit relatively small d-spacing (e.g., a d-spacing value of 10 nm or less). Due to their properties, the polymers described herein are useful in a variety of applications including functional materials and biomedical applications.

  本发明提供聚合物及其制备方法。在某些实施方案中，聚合物包含丙烯酸酯重复单元，这些单元经过衍生化（如还原和/或取代）后形成新的聚合物结构。在某些实施例中，本文所述聚合物可自组装形成定义明确的纳米结构。在某些情况下，纳米结构的 d 间距相对较小（例如，d 间距值为 10 nm 或更小）。由于其特性，本文所述聚合物可用于多种应用，包括功能材料和生物医学应用。