1-(2'-Dimethylamino-ethyl-1'-amino)-anthrachinon | 14956-33-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 1-(2'-Dimethylamino-ethyl-1'-amino)-anthrachinon
• 英文别名: 1-[2-(Dimethylamino)ethylamino]anthracene-9,10-dione
• CAS: 14956-33-3
• 化学式: C₁₈H₁₈N₂O₂
• 分子量: 294.353
• InChiKey: QSACIMBCMUVJQP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  49.4
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  1-(2'-Dimethylamino-ethyl-1'-amino)-anthrachinon 、 氯化苄 以 乙醇 为溶剂， 反应 24.0h， 以80%的产率得到
  参考文献：
  名称：

  Quaternary ammonium salt-based chromogenic and fluorescent chemosensors for fluoride ions

  摘要：

  Chemosensors 5-7 possessing a quaternary ammonium cation (for electrostatic interactions) and an N-H group(s) (for H-bonding) as recognition sites and an anthracene-9,10-dione as both a chromogenic and fluorescent moiety exhibit absorption and emission changes with fluoride ions only. No significant response to other anions such as Cl-, Br-, I-, NO3-, CH3COO-, HSO4-, H2PO4- and ClO4- is observed. The dual emission at lambda(max) 580 nm (free 5/6) and lambda(max) 510 and 540 nm (5/6 + F-) in chemosensors 5 and 6 enables ratiometric analysis of fluoride ions. (C) 2008 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2008.04.147

文献信息

• Fluorochromes for organelle tracing and multi-color imaging
  申请人：Patton Wayne Forrest

  公开号：US20100062429A1

  公开（公告）日：2010-03-11

  Provided are compounds, methods and kits for identifying in cells of interest organelles including nuclei and a wide variety of organelles other than nuclei (non-nuclear organelles), as well as cell regions or cell domains. These compounds and methods can be used with other conventional detection reagents for identifying the location or position or quantity of organelles and even for distinguishing between organelles in cells of interest.

  提供了一些化合物、方法和试剂盒，用于鉴定感兴趣的细胞中的细胞器，包括细胞核和各种非细胞核细胞器，以及细胞区域或细胞域。这些化合物和方法可以与其他常规检测试剂一起使用，用于确定细胞器的位置、数量，甚至用于区分感兴趣的细胞中的细胞器。