1,4-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyridine-3-carbonitrile | 1189820-05-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: 1,4-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyridine-3-carbonitrile
• 英文别名: 1,4-dimethyl-2,6-dioxo-3H-pyridine-3-carbonitrile
• CAS: 1189820-05-0
• 化学式: C₈H₈N₂O₂
• 分子量: 164.164
• InChiKey: XBPVHXVJJROVKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.4
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  61.2
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Dispers-reactive dyes containing acetoxymethylsulfone or vinylsulfone and their process
  申请人：——

  公开号：US20040077846A1

  公开（公告）日：2004-04-22

  The present invention relates to water insoluble disperse-reactive dyes expressed by the formula (3) and (4) and to their preparation, (3) (4) wherein each of Ar 1 and Ar 2 represents aryl or benzothiazole group, and each of R, R 1 , R 2 , and R 3 independently represents hydrogen, alkyl, alkoxy, cyanoalkyl or aminoacetyl group. 1

  本发明涉及由式 (3) 和 (4) 表示的水不溶性分散反应染料及其制备方法，(3) (4) 其中 Ar 1 和 Ar 2 代表芳基或苯并噻唑基团，R、R 1 , R 2 和 R 3 分别代表氢、烷基、烷氧基、氰基烷基或氨基乙酰基。 1
• COMPOSITIONS AND METHODS FOR INHIBITION OF HEPATOCYTE GROWTH FACTORY RECEPTOR C-MET SIGNALING
  申请人：The United States Of America, As Represented By The Secretary, Department Of Health & Human Services

  公开号：EP2271620A1

  公开（公告）日：2011-01-12
• COMPOSITIONS AND METHODS FOR INHIBITION OF HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET SIGNALING
  申请人：Bottaro Donald P.

  公开号：US20110190295A1

  公开（公告）日：2011-08-04

  Derivatives and analogs of inhibitors of receptor tyrosine kinase c-Met, pharmaceutical compositions containing derivatives and analogs of c-Met inhibitors are provided. Methods of making derivatives and analogs of c-Met inhibitors and methods of use thereof are provided.
• US6884876B2
  申请人：——

  公开号：US6884876B2

  公开（公告）日：2005-04-26
• US8754081B2
  申请人：——

  公开号：US8754081B2

  公开（公告）日：2014-06-17