3-[(2-Bromophenyl)sulfanyl]-2,3-dihydro-1H-1lambda~6~-thiophene-1,1-dione | 194085-42-2

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 3-[(2-Bromophenyl)sulfanyl]-2,3-dihydro-1H-1lambda~6~-thiophene-1,1-dione
• 英文别名: 3-(2-bromophenyl)sulfanyl-2,3-dihydrothiophene 1,1-dioxide
• CAS: 194085-42-2
• 化学式: C₁₀H₉BrO₂S₂
• 分子量: 305.216
• InChiKey: PCDRKSWFFFIELF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  67.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-[(2-Bromophenyl)sulfanyl]-2,3-dihydro-1H-1lambda~6~-thiophene-1,1-dione 在 N-溴代丁二酰亚胺(NBS) 、 偶氮二异丁腈 、 三正丁基氢锡 作用下， 以 甲苯 、 苯 为溶剂， 反应 5.5h， 生成 2-Phenyl-3a,4,10,10a-tetrahydro-9-thia-2-aza-cyclopenta[b]fluorene-1,3-dione
  参考文献：
  名称：

  Preparation and Reactions of Benzofurano-, Indolo-, and Benzothieno-3-sulfolenes

  摘要：

  Benzofurano-, N-tosylindolo-, and benzothieno-3-sulfolenes have been prepared efficiently via their dihydro analogues. These fused 3-sulfolenes serve as ideal precursors for the corresponding heteroaromatic o-quinodimethanes. Derivatives of these 3-sulfolenes bearing bromo or alkyl group substitution from which substituted heteroaromatic o-quinodimethanes are generated have also been synthesized.

  DOI：

  10.1021/jo980044e
• 作为产物：
  描述：

  2-溴硫代苯酚 在 吡啶 、 N-溴代丁二酰亚胺(NBS) 作用下， 以 二氯甲烷 为溶剂， 反应 73.0h， 生成 3-[(2-Bromophenyl)sulfanyl]-2,3-dihydro-1H-1lambda~6~-thiophene-1,1-dione
  参考文献：
  名称：

  Preparation and Reactions of Benzofurano-, Indolo-, and Benzothieno-3-sulfolenes

  摘要：

  Benzofurano-, N-tosylindolo-, and benzothieno-3-sulfolenes have been prepared efficiently via their dihydro analogues. These fused 3-sulfolenes serve as ideal precursors for the corresponding heteroaromatic o-quinodimethanes. Derivatives of these 3-sulfolenes bearing bromo or alkyl group substitution from which substituted heteroaromatic o-quinodimethanes are generated have also been synthesized.

  DOI：

  10.1021/jo980044e

文献信息

• Preparation of benzofurano-, benzothieno-, indolo-3-sulfolenes as precursors for heteroaromatic o-quinodimethanes
  作者：Chung-Wen Ko、Ta-shue Chou

  DOI：10.1016/s0040-4039(97)01183-0

  日期：1997.7

  Efficient routes have been developed for the synthesis of benzofurano-3-sulfolene 16, benzofurano-3-sulfolene 16, and N-tosylindolo-3-sulfolene 18. These compounds are ideal precursors for the corresponding heteroaromatic alpha-quinodimethanes. (C) 1997 Elsevier Science Ltd.
• Preparation and Reactions of Benzofurano-, Indolo-, and Benzothieno-3-sulfolenes
  作者：Chung-Wen Ko、Ta-shue Chou

  DOI：10.1021/jo980044e

  日期：1998.7.1

  Benzofurano-, N-tosylindolo-, and benzothieno-3-sulfolenes have been prepared efficiently via their dihydro analogues. These fused 3-sulfolenes serve as ideal precursors for the corresponding heteroaromatic o-quinodimethanes. Derivatives of these 3-sulfolenes bearing bromo or alkyl group substitution from which substituted heteroaromatic o-quinodimethanes are generated have also been synthesized.