methyl (2-chloroethyl)methylcarbamate | 10230-46-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: methyl (2-chloroethyl)methylcarbamate
• 英文别名: methyl N-(2-chloroethyl)-N-methylcarbamate
• CAS: 10230-46-3
• 化学式: C₅H₁₀ClNO₂
• 分子量: 151.593
• InChiKey: RASAJAJIGMQFBL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• N,N-BIS(2-DIALKYLPHOSPHINOETHYL)AMINE-BORANE COMPLEX AND PRODUCTION METHOD THEREFOR, AND METHOD FOR PRODUCING RUTHENIUM COMPLEX CONTAINING N,N-BIS(2-DIALKYLPHOSPHINOETHYL)AMINE AS LIGAND
  申请人：Takasago International Corporation

  公开号：US20190040090A1

  公开（公告）日：2019-02-07

  The purpose of the present invention is to provide an N,N-bis(2-dialkylphosphinoethyl)amine-borane complex which is a ruthenium complex that exhibits excellent catalytic activity in a hydrogenation reaction, etc., and a production method therefor, and a method for efficiently producing a ruthenium complex containing N,N-bis(2-dialkylphosphinoethyl)amine as a ligand. The present invention is capable of efficiently producing an amine-borane complex (3) by reacting an oxazolidinone compound (1) with a dialkylphosphine-borane compound (2) in the presence of a base. The present invention is also capable of efficiently producing a ruthenium complex (5) by reacting the amine-borane complex (3) with a ruthenium compound (4) in the presence of an amine. (In the formula, a solid line, a dashed line, B, C, H, L 1 -L 3 , LG, n, N, O, P, Ru, X, and R 1 -R 10 are as defined in the description.)

  本发明的目的是提供一种N,N-双(2-二烷基膦基乙基)胺硼烷配合物，它是一种在氢化反应中表现出优异催化活性的钌配合物等，以及其生产方法，以及一种有效生产含有N,N-双(2-二烷基膦基乙基)胺作为配体的钌配合物的方法。本发明能够通过在碱存在下将噁唑烷酮化合物(1)与二烷基膦硼烷化合物(2)反应来有效生产胺硼烷配合物(3)。本发明还能够通过在胺存在下将胺硼烷配合物(3)与钌化合物(4)反应来有效生产钌配合物(5)。
• N-N-bis(2-dialkylphosphinoethyl)amine-borane complex and production method therefor, and method for producing ruthenium complex containing N,N-bis(2-dialkylphosphinoethyl)amine as ligand
  申请人：Takasago International Corporation

  公开号：US10407448B2

  公开（公告）日：2019-09-10

  The purpose of the present invention is to provide an N,N-bis(2-dialkylphosphinoethyl)amine-borane complex which is a ruthenium complex that exhibits excellent catalytic activity in a hydrogenation reaction, etc., and a production method therefor, and a method for efficiently producing a ruthenium complex containing N,N-bis(2-dialkylphosphinoethyl)amine as a ligand. The present invention is capable of efficiently producing an amine-borane complex (3) by reacting an oxazolidinone compound (1) with a dialkylphosphine-borane compound (2) in the presence of a base. The present invention is also capable of efficiently producing a ruthenium complex (5) by reacting the amine-borane complex (3) with a ruthenium compound (4) in the presence of an amine. (In the formula, a solid line, a dashed line, B, C, H, L1-L3, LG, n, N, O, P, Ru, X, and R1-R10 are as defined in the description.)

  本发明的目的是提供一种N,N-双(2-二烷基膦乙基)胺硼烷络合物，它是一种在氢化反应等中表现出优异催化活性的钌络合物，并提供其生产方法，以及一种高效生产含有N,N-双(2-二烷基膦乙基)胺作为配体的钌络合物的方法。本发明能够通过在碱存在下使噁唑烷酮化合物（1）与二烷基膦硼烷化合物（2）反应，高效生产胺硼烷配合物（3）。本发明还能在胺存在的情况下，通过胺硼烷络合物（3）与钌化合物（4）反应，高效生产钌络合物（5）。 (式中，实线、虚线、B、C、H、L1-L3、LG、n、N、O、P、Ru、X 和 R1-R10 如说明中所定义）。
• US4607051A
  申请人：——

  公开号：US4607051A

  公开（公告）日：1986-08-19