cresyl violet | 24350-68-3

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: cresyl violet
• 英文别名: 5-Imino-5H-benzo[a]phenoxazin-9-amine；9-iminobenzo[a]phenoxazin-5-amine
• CAS: 24350-68-3
• 化学式: C₁₆H₁₁N₃O
• 分子量: 261.283
• InChiKey: QSFBNJFFCSWAQO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  20
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  71.5
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• NUCLEIC ACID AMPLIFICATION AND SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES
  申请人：Xie Xiaoliang Sunney

  公开号：US20130053252A1

  公开（公告）日：2013-02-28

  In general, the invention features methods and systems for sequencing of nucleic acids based on the measurement of the incorporation of fluorogenic nucleotides in microreactors. The invention provides numerous advantages over previous systems such as unambiguous determination of sequence, fast cycle time, long read lengths, low overall cost of reagents, low instrument cost, and high throughput. The invention also features methods and kits for nucleic acid amplification. The amplification and sequencing aspects of the invention may or may not be employed in conjunction with one another. The invention also features fluorogenic nucleotides that may be used in the sequencing methods of the invention.

  一般来说，该发明涉及基于在微反应器中测量荧光核苷酸的结合而进行核酸测序的方法和系统。该发明相比先前系统具有诸多优势，如序列的明确确定、快速循环时间、长读取长度、低试剂总成本、低仪器成本和高吞吐量。该发明还涉及核酸扩增的方法和试剂盒。该发明的扩增和测序方面可以单独或结合使用。该发明还涉及可用于该测序方法的荧光核苷酸。
• Reagent, reagent kit and analyzing method
  申请人：SYSMEX CORPORATION

  公开号：EP1918709A1

  公开（公告）日：2008-05-07

  A method for analyzing platelet is described. In the method, a measurement sample is prepared by mixing a sample and a dye for staining platelet. The dye is selected from the group consisting of Capri blue, Nile blue and brilliant cresyl blue. By irradiating cells in the measurement sample with light, scattered light and fluorescence emitted from the cells is measured. The platelet is detected on the basis of the scattered light and the fluorescence. A reagent kite and a reagent are also described.

  本文描述了一种分析血小板的方法。在该方法中，通过混合样本和用于染色血小板的染料来制备测量样本。染料选自卡普里蓝、尼罗蓝和亮甲酚蓝。用光照射测量样本中的细胞，测量细胞发出的散射光和荧光。根据散射光和荧光检测血小板。 此外，还介绍了一种试剂风筝和一种试剂。
• REAGENT AND REAGENT KIT FOR ANALYSIS OF PRIMITIVE LEUKOCYTE
  申请人：Sysmex Corporation

  公开号：EP2166354A1

  公开（公告）日：2010-03-24

  The present invention provides a reagent for analysis of immature leukocytes comprising: a surfactant which can damage cell membranes of erythrocytes and mature leukocytes, a solubilizing agent which can shrink the damaged blood cells and at least one dye for staining nucleic acid selected from the dyes of the formulae (I) and (II), wherein X- is an anion.

  本发明提供了一种用于分析未成熟白细胞的试剂，包括 一种表面活性剂，可破坏红细胞和成熟白细胞的细胞膜、 可使受损血细胞缩小的增溶剂，以及 至少一种用于染色核酸的染料，选自式 (I) 和 (II) 染料，其中 X- 是阴离子。
• PLATELET MEASUREMENT REAGENT, PLATELET MEASUREMENT REAGENT KIT, AND PLATELET MEASUREMENT METHOD
  申请人：Sysmex Corporation

  公开号：EP2273264A1

  公开（公告）日：2011-01-12

  A reagent for measuring platelets comprising Nile Blue hydrogensulfate, or Nile Blue and an acid, a reagent kit for measuring platelets comprising the reagent for measuring platelets, and a method for measuring platelets using the reagent or reagent kit.

  一种测量血小板的试剂，包含硫酸氢尼罗蓝或尼罗蓝和一种酸；一种测量血小板的试剂盒，包含该测量血小板的试剂；以及一种使用该试剂或试剂盒测量血小板的方法。
• METHODS AND COMPOSITIONS FOR CONTINUOUS SINGLE-MOLECULE NUCLEIC ACID SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES
  申请人：President and Fellows of Harvard College

  公开号：EP2315857A1

  公开（公告）日：2011-05-04