| 80459-34-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• CAS: 80459-34-3
• 化学式: C₁₀H₁₆O₄
• 分子量: 200.235
• InChiKey: IGOBMABWRSCIAA-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 溴 作用下， 以 四氯化碳 为溶剂， 反应 8.0h， 以68%的产率得到Dimethyl 2-bromo-2-(1-bromobutyl)butanedioate
  参考文献：
  名称：

  Bromine-Induced Facile Synthesis of Butenolides and Spirobutenolides from Sterically Congested Tetrasubstituted Dialkyl Alkylidene Succinates

  摘要：

  从立体拥挤的四取代二烷基烯基琥珀酸酯出发，通过溴诱导的脱烷基化区域选择性分子内环化及脱溴化氢反应途径，已经证明了合成几种二烷基取代的丁烯内酯和螺丁烯内酯并生成四级碳中心的简便通用方法。对形成丁烯内酯的机理方面也进行了简要描述。

  DOI：

  10.1055/s-0029-1219233

文献信息

• RESORBABLE NONWOVEN POUCHES FOR MEDICAL DEVICE IMPLANTS
  申请人：Tepha, Inc.

  公开号：EP3897452A1

  公开（公告）日：2021-10-27
• [EN] RESORBABLE NONWOVEN POUCHES FOR MEDICAL DEVICE IMPLANTS<br/>[FR] POCHES RÉSORBABLES NON TISSÉES POUR IMPLANTS DE DISPOSITIFS MÉDICAUX
  申请人：TEPHA INC

  公开号：WO2020131172A1

  公开（公告）日：2020-06-25

  Nonwoven resorbable pouches that at least partially enclose implantable medical devices and improved methods for producing the implantable medical device pouches are described. The nonwoven pouches may comprise one or more drugs. Implantable medical devices that are placed in the pouches prior to implantation are prevented from migrating from the site of implantation by tissue ingrowth into the pouch. Antibiotics may be incorporated into the pouches to prevent post-operative infections. The pouches may be formed in fewer steps than conventional pouches, and without polymer coatings. Nonwoven pouches can be formed in one step by dry spinning instead of using multiple processing steps. In embodiments, the nonwoven pouches are smoother on the inside than the outside to tightly fit the implantable medical devices internally while encouraging external tissue ingrowth. In embodiments, the nonwoven pouches eliminate the use of knitted or woven multifilament fibers that can trap bacteria and result in post-operative infection.
• [EN] BREAST IMPLANT WRAPS TO LIMIT MOVEMENT OF BREAST IMPLANTS AND RELATED METHODS<br/>[FR] ENVELOPPES D'IMPLANTS MAMMAIRES POUR LIMITER LE MOUVEMENT D'IMPLANTS MAMMAIRES ET MÉTHODES ASSOCIÉES
  申请人：TEPHA INC

  公开号：WO2021108162A1

  公开（公告）日：2021-06-03

  Described herein are breast implant fixation devices for use in breast reconstruction and breast augmentation. Novel wraps are designed to avert lateral displacement and bottoming out of breast implants, reduce capsular contraction and implant extrusion, eliminate skin indentations and ripples caused by breast implants, and reduce or eliminate palpability. The wraps are adapted to securely fold around the breast implants, limiting relative movement between the wrap and breast implant and reducing wrinkles. Tissue in-growth into the wraps limits movement of the wrap-breast implant assembly and thereby limits movement of the breast implant.