diethyl 2,2'-[2-(5-(dimethylamino)naphthalene-1-sulfonamido)ethylazanediyl]diacetate | 1392423-30-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: diethyl 2,2'-[2-(5-(dimethylamino)naphthalene-1-sulfonamido)ethylazanediyl]diacetate
• 英文别名: Ethyl 2-[2-[[5-(dimethylamino)naphthalen-1-yl]sulfonylamino]ethyl-(2-ethoxy-2-oxoethyl)amino]acetate
• CAS: 1392423-30-1
• 化学式: C₂₂H₃₁N₃O₆S
• 分子量: 465.571
• InChiKey: YSFSVHSYMFVFJT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  32
• 可旋转键数：
  14
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  114
• 氢给体数：
  1
• 氢受体数：
  9

反应信息

• 作为产物：
  描述：

  N-tert-butoxycarbonyl-N',N'-bis(ethoxycarbonylmethyl)ethylenediamine 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 15.08h， 生成 diethyl 2,2'-[2-(5-(dimethylamino)naphthalene-1-sulfonamido)ethylazanediyl]diacetate
  参考文献：
  名称：

  An inorganic phosphate (Pi) sensor triggers ‘turn-on’ fluorescence response by removal of a Cu2+ ion from a Cu2+-ligand sensor: determination of Pi in biological samples

  摘要：

  A fluorescent ligand that displays a high selectivity for Cu2+ has been synthesized. On complexation with Cu2+, the fluorescence of the ligand is quenched. Inorganic phosphate ions decomplex Cu2+ displaying a fluorescence enhancement that can even be seen with naked eyes. The method was successfully used in quantitative determination of inorganic phosphates in serum, urine, and saliva samples. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2012.06.014