| 1242142-87-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 香豆素及其衍生物
• CAS: 1242142-87-5
• 化学式: C₂₁H₁₂O₇
• 分子量: 376.322
• InChiKey: DYOMMMPSZDEESJ-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  、 N,N-二甲基乙二胺 在 silica gel 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 以89%的产率得到
  参考文献：
  名称：

  Benzoxazine and Benzodioxine as Indole Isosteres in Indolocarbazoles Series: Synthesis and Biological Evaluation

  摘要：

  New series of structure based on original benzodioxine and benzoxazine heterocycles were prepared leading to potential anticancer lead compounds. In this paper, we described a convenient approach via a Diels-Alder cycloaddition in order to efficiently provide three new indole isosteres in indolocarbazoles series. Their first cytotoxic evaluation was also reported.

  DOI：

  10.2174/157017810790796291
• 作为产物：
  描述：

  在 乙酸酐 作用下， 反应 4.0h， 生成
  参考文献：
  名称：

  Benzoxazine and Benzodioxine as Indole Isosteres in Indolocarbazoles Series: Synthesis and Biological Evaluation

  摘要：

  New series of structure based on original benzodioxine and benzoxazine heterocycles were prepared leading to potential anticancer lead compounds. In this paper, we described a convenient approach via a Diels-Alder cycloaddition in order to efficiently provide three new indole isosteres in indolocarbazoles series. Their first cytotoxic evaluation was also reported.

  DOI：

  10.2174/157017810790796291