(E)-5-tert-butoxycarbonylamino-2-eth-(Z)-ylidenepent-3-enoic acid methyl ester | 1250265-94-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (E)-5-tert-butoxycarbonylamino-2-eth-(Z)-ylidenepent-3-enoic acid methyl ester
• CAS: 1250265-94-1
• 化学式: C₁₃H₂₁NO₄
• 分子量: 255.314
• InChiKey: GKFJCMPZFPFXJS-BGDUUMEQSA-N

反应信息

• 作为反应物：
  描述：

  (E)-5-tert-butoxycarbonylamino-2-eth-(Z)-ylidenepent-3-enoic acid methyl ester 在 三氟乙酸 作用下， 以 二氯甲烷 为溶剂， 反应 0.25h， 生成
  参考文献：
  名称：

  Synthesis of a new family of 2-ethylidene-γ-unsaturated δ-amino esters via microwave activated Stille coupling

  摘要：

  A simple approach to a new family of enantiomerically enriched polyunsaturated t-Boc-protected-delta-amino esters is described, via microwave promoted Stille coupling of (Z)-methyl-2-bromobutenoate with stannylated allylamines. The reaction conditions are mild and selective and disclose a simple way to 1-substituted butenoates of defined geometry.

  DOI：

  10.1007/s00726-009-0392-y
• 作为产物：
  描述：

  氨甲酸,[3-(三丁基甲锡烷基)-2-丙烯基]-,1,1-二甲基乙基酯,(E)- 、 (E)-methyl α-bromocrotonate 在 四(三苯基膦)钯 作用下， 以 甲苯 为溶剂， 反应 0.5h， 以76%的产率得到(E)-5-tert-butoxycarbonylamino-2-eth-(Z)-ylidenepent-3-enoic acid methyl ester
  参考文献：
  名称：

  Synthesis of a new family of 2-ethylidene-γ-unsaturated δ-amino esters via microwave activated Stille coupling

  摘要：

  A simple approach to a new family of enantiomerically enriched polyunsaturated t-Boc-protected-delta-amino esters is described, via microwave promoted Stille coupling of (Z)-methyl-2-bromobutenoate with stannylated allylamines. The reaction conditions are mild and selective and disclose a simple way to 1-substituted butenoates of defined geometry.

  DOI：

  10.1007/s00726-009-0392-y