3-(anthracen-2-yl)acrylic acid | 75802-28-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 蒽
• 英文名称: 3-(anthracen-2-yl)acrylic acid
• 英文别名: 3t-[2]anthryl-acrylic acid；3t-[2]Anthryl-acrylsaeure；2-anthracene acrylic acid；(E)-3-anthracen-2-ylprop-2-enoic acid
• CAS: 75802-28-7
• 化学式: C₁₇H₁₂O₂
• 分子量: 248.281
• InChiKey: IGDIDTJJFQYIRV-SOFGYWHQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  19
• 可旋转键数：
  2
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3-(anthracen-2-yl)acrylic acid 以84%的产率得到
  参考文献：
  名称：

  ARJUNAN P.; SHYMASUNDAR N.; BERLIN K. D.; NAJJAR D.; ROCKLEY M. G., J. ORG. CHEM., 1981, 46, NO 3, 626-629

  摘要：

  DOI：
• 作为产物：
  描述：

  2-蒽甲醛 在 potassium trimethylsilonate 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 反应 20.0h， 生成 3-(anthracen-2-yl)acrylic acid
  参考文献：
  名称：

  脂肪酸代谢的荧光形态底物：哺乳动物中链酰基辅酶A脱氢酶的高灵敏度探针。

  摘要：

  DOI：

  10.1002/anie.200502675

文献信息

• Etienne et al., Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1959, vol. 249, p. 708
  作者：Etienne et al.

  DOI：——

  日期：——
• Phytogeographic relationships between neotropical and African-Madagascan pteridophytes
  作者：Robbin C. Moran、Alan R. Smith

  DOI：10.1007/bf02812704

  日期：2001.4

  Moran. R. C. (The New York Botanical Garden, Bronx, NY 10458-5126, U.S.A.) & A. R. Smith (University Herbarium, University of California, 1001 Valley Life Sciences Bldg. #2465, Berkeley, CA 94720-2465, U.S.A.). Phytogeographic relationships between neotropical and African-Madagascan pteridophytes. Brittonia 53: 304-351. 2001.-The purpose of this study is to determine the floristic affinities of pteridophytes between the Neotropics and Africa-Madagascar and examine how these affinities might have arisen. We present an annotated list that contains two kinds of affinities: 1) species in common between both regions (excluding pantropical species) and 2) species pairs (or clusters of species pairs) where one of the species (or infrageneric group) occurs in the Neotropics and the other in Africa and/or Madagascar. There are 114 examples on the list, of which 27 are same-species and 87 are species pairs or closely related taxa at some infrageneric level. About 13% of the African pteridoflora and 14% of the Madagascan pteridoflora show affinities with the Neotropics. To determine how these similarities might have originated, we assess three hypotheses: 1) the boreotropics hypothesis, 2) continental drift, and 3) long-distance dispersal. The boreotropics hypothesis is difficult to assess without further phylogenetic information on the groups to which the species belong. Continental drift seems to best explain one example in the geologically old family Schizaeaceae (species in Anemia subgen. Coptophyllum sect. Tomentosae). Nearly all the other examples seem best explained by long-distance dispersal because they belong to families that first appeared during the Paleocene, more than 30 million years after drift had effectively separated South America and Africa. Most of the dispersal events appear to have taken place from the Neotropics to Africa-Madagascar but recent African extinctions may have obscured directionality. Species with green spores or gemmiferous gametophytes were slightly overrepresented on the list compared to pteridophytes as a whole.
• SALTS OF PAROXETINE
  申请人：SMITHKLINE BEECHAM PLC

  公开号：EP1091958A1

  公开（公告）日：2001-04-18
• [EN] SALTS OF PAROXETINE<br/>[FR] SELS DE PAROXETINE
  申请人：SMITHKLINE BEECHAM PLC

  公开号：WO2000001692A1

  公开（公告）日：2000-01-13

  Piperidine compounds, processes for preparing them, pharmaceutical compositions comprising them and their use in therapy are disclosed.
• [EN] FLUOROGENIC PROBES FOR MEDIUM CHAIN ACYL-COA DEHYDROGENASE ( MCAD )<br/>[FR] SONDES FLUOROGENES POUR ACYL-COA DESHYDROGENASE DES ACIDES GRAS A CHAINE MOYENNE (MCAD)
  申请人：UNIV COLUMBIA

  公开号：WO2007022263A1

  公开（公告）日：2007-02-22

  [EN] The present invention relates to compounds useful for detecting the activity of human MCAD, compounds useful for competitively inhibiting human MCAD, as well as methods of manufacture thereof .
  [FR] La présente invention concerne des composés convenant à la détection de l'activité du MCAD chez l'homme, des composés convenant à l'inhibition compétitive du MCAD chez l'homme, ainsi que des procédés de fabrication correspondants.