8-(1-pyrenemethoxy)-3,6-(dioxa)octa-1-amine | 1235982-96-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: 8-(1-pyrenemethoxy)-3,6-(dioxa)octa-1-amine
• CAS: 1235982-96-3
• 化学式: C₂₃H₂₅NO₃
• 分子量: 363.456
• InChiKey: HYVOCJJHBVLLTJ-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  8-(1-pyrenemethoxy)-3,6-(dioxa)octa-1-amine 、 6A,6E-di(thioacetic acid) γ-CyD 在 1-羟基苯并三唑 、 N,N'-二环己基碳二亚胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 2.0h， 以6.14%的产率得到di-6A,6E-deoxy-6A,6E-[{8-(1-pyrenemethoxy)-3,6-(dioxa)-octa-1-amino}-(thioacetyl)]-γ-CyD
  参考文献：
  名称：

  Double stranded DNA discrimination by di-pyrene modified γ-cyclodextrin

  摘要：

  Neutral fluorescent active di-pyrene modified gamma-cyclodextrin (1) was synthesized in order to discriminate with single and double strand DNA (ssDNA and dsDNA, respectively) with high selectivity. The binding and selectivity of 1 for dsDNA was indicated by increase of the fluorescent intensity in an addition of dsDNA. On the other hand, an increase of fluorescent intensity of 1 was not recognized in an addition of ssDNA. (C) 2010 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.bmcl.2010.04.066