1,4-Dihydropyridazin-3,6-dicarbonsaeure-dimethylester | 90007-72-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,4-Dihydropyridazin-3,6-dicarbonsaeure-dimethylester
• 英文别名: 3,6-Dimethoxycarbonyl-1,4-dihydro-pyridazin；1,4-dihydro-pyridazine-3,6-dicarboxylic acid dimethyl ester；Dimethyl 1,4-dihydropyridazine-3,6-dicarboxylate
• CAS: 90007-72-0
• 化学式: C₈H₁₀N₂O₄
• 分子量: 198.178
• InChiKey: SLUVGXLTAKSSKG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  77
• 氢给体数：
  1
• 氢受体数：
  6

反应信息

• 作为产物：
  描述：

  dimethyl pyridazine-3,6-dicarboxylate 以 acetate buffer 为溶剂， 以100%的产率得到1,4-Dihydropyridazin-3,6-dicarbonsaeure-dimethylester
  参考文献：
  名称：

  Activated pyrroles from pyridazines: nitrogen extrusion by electroreduction

  摘要：

  The bielectronic electrochemical reduction of pyridazines, substituted by electron-withdrawing groups, leads to their corresponding 1,2-dihydro derivatives. Depending on the nature of the ring substitution, these intermediates can either rearrange into 1,4-dihydropyridazine isomers or be further electrochemically reduced into activated pyrroles. (C) 2000 Published by Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)02155-3

文献信息

• Dihydropyridazine antioxidant sunscreens
  申请人：ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

  公开号：US11325925B2

  公开（公告）日：2022-05-10

  Herein polymers and particles which comprise a plurality of dihydropyridazine or hydropyridazine functional groups are described. Methods for their formation and specific monomers which may be used in their formation are also described. The polymers and particles are UV absorbing, hydrogen-donor antioxidant materials which signal a depletion of antioxidant ability by a decrease in visible fluorescence. These polymers and particles may be used as UV protectants for a variety of materials and substrates and may even be used in a topically applied formulation for human skin.

  本文描述了包含多个二氢哒嗪或氢哒嗪官能团的聚合物和微粒。此外，还介绍了形成它们的方法和可用于形成它们的特定单体。这些聚合物和微粒是紫外线吸收、氢供体抗氧化材料，可通过可见荧光的减少来显示抗氧化能力的衰竭。这些聚合物和微粒可用作各种材料和基质的紫外线防护剂，甚至可用于人体皮肤的外用配方。
• Vinyl- und Ethinylborane als Dienophile in derDiels-Alder-Cycloaddition mit inversem Elektronenbedarf. Vinyl- and Ethynylboranes as Dienophiles in theDiels-Alder-Cycloaddition with Inverse Electron Demand
  作者：Gunther Seitz、Frank Haenel

  DOI：10.1002/ardp.19943271014

  日期：——
• Seitz Gunther, Haenel Frank, Arch. Pharm, 327 (1994) N 10, S 673-675
  作者：Seitz Gunther, Haenel Frank

  DOI：——

  日期：——
• DIHYDROPYRIDAZINE ANTIOXIDANT SUNSCREENS
  申请人：ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA

  公开号：US20200270281A1

  公开（公告）日：2020-08-27

  Herein polymers and particles which comprise a plurality of dihydropyridazine or hydropyridazine functional groups are described. Methods for their formation and specific monomers which may be used in their formation are also described. The polymers and particles are UV absorbing, hydrogen-donor antioxidant materials which signal a depletion of antioxidant ability by a decrease in visible fluorescence. These polymers and particles may be used as UV protectants for a variety of materials and substrates and may even be used in a topically applied formulation for human skin.
• [EN] DIHYDROPYRIDAZINE ANTIOXIDANT SUNSCREENS<br/>[FR] ÉCRANS SOLAIRES ANTIOXYDANTS À BASE DE DIHYDROPYRIDAZINE
  申请人：UNIV ARIZONA

  公开号：WO2019046848A1

  公开（公告）日：2019-03-07

  Herein polymers and particles which comprise a plurality of dihydropyridazine or hydropyridazine functional groups are described. Methods for their formation and specific monomers which may be used in their formation are also described. The polymers and particles are UV absorbing, hydrogen-donor antioxidant materials which signal a depletion of antioxidant ability by a decrease in visible fluorescence. These polymers and particles may be used as UV protectants for a variety of materials and substrates and may even be used in a topically applied formulation for human skin.