3-fluorobenzyl acrylate | 144261-44-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-fluorobenzyl acrylate
• 英文别名: (3-Fluorophenyl)methyl prop-2-enoate
• CAS: 144261-44-9
• 化学式: C₁₀H₉FO₂
• 分子量: 180.179
• InChiKey: RFWOWJSMEKPJKD-UHFFFAOYSA-N

物化性质

• 沸点：
  227.7±15.0 °C(Predicted)
• 密度：
  1.140±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3-fluorobenzyl acrylate 、 在 silver(I) acetate 、 palladium diacetate 、 N-乙酰甘氨酸 作用下， 以 2,2,2-三氟乙醇 为溶剂， 以47%的产率得到
  参考文献：
  名称：

  通过远端 C−H 活化合成二茂铁 1,3-衍生物**

  摘要：

  尽管过渡金属催化已发展成为一种强大的催化平台，但其在二茂铁远端 C−H 官能化中的应用直到最近才得到解决。在这里，在可移除的导向基团的帮助下，Pd II /单-N-保护的氨基酸配体催化的二茂铁远端C(3)-H官能化已被证明，同时经历二茂铁附加的12元环状过渡态。

  DOI：

  10.1002/anie.202305278
• 作为产物：
  描述：

  丙烯酸 、 间氟氯苄 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 3.0h， 生成 3-fluorobenzyl acrylate
  参考文献：
  名称：

  镍催化的炔烃和缺电子烯烃插入未激活的sp3 C中？H债券

  摘要：

  不饱和系统，例如炔烃和烯烃进未活化的SP的插入3 Ç  H键仍然是一个未知的问题。本文我们通过成功地掺入各种官能炔烃和缺电子烯烃的成未活化SP解决这个问题3 Ç 新戊酸衍生物的H键具有优良的顺式和直链选择性。事实证明，强螯合的8-氨基喹啉导向基团对这些插入反应有利，而空气稳定且廉价的Ni II盐已被用作活性催化剂。

  DOI：

  10.1002/chem.201501962

文献信息

• Rhodium-Catalyzed <i>meta</i> -C−H Functionalization of Arenes
  作者：Milan Bera、Soumitra Agasti、Rajdip Chowdhury、Rahul Mondal、Debasis Pal、Debabrata Maiti

  DOI：10.1002/anie.201701579

  日期：2017.5.2

  Rhodium‐catalyzed ortho‐C−H functionalization is well known in the literature. Described herein is the Xphos‐supported rhodium catalysis of meta‐C−H olefination of benzylsulfonic acid and phenyl acetic acid frameworks with the assistance of a para‐methoxy‐substituted cyano phenol as the directing group. Complete mono‐selectivity is observed for both scaffolds. A wide range of olefins and functional groups

  铑催化的邻-C-H官能化在文献中是众所周知的。本文描述的是Xphos负载的铑催化苄基磺酸和苯基乙酸骨架的间-C H烯化反应，并以对甲氧基取代的氰基苯酚为指导基团。两种支架均观察到完全的单选择性。在此方案中，可以耐受与芳烃连接的各种烯烃和官能团。
• Polymer compound, film obtained by hardening this polymer compound and electronic device comprising this film
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US10676554B2

  公开（公告）日：2020-06-09

  A polymer compound comprising a repeating unit having at least one group selected from the group consisting of a blocked isocyanato group and a blocked isothiocyanato group, a repeating unit having at least one group selected from the group consisting of a hydroxy group and a carboxy group and a repeating unit represented by the following formula (1), wherein the content of the repeating unit having at least one group selected from the group consisting of a blocked isocyanato group and a blocked isothiocyanato group in the polymer compound is 1% by mol or more and 30% by mol or less when the total content of all repeating units contained in the above-described polymer compound is taken as 100% by mol: in the formula (1), R2, R2 and R3 each independently represent a hydrogen atom or a methyl group.

  一种聚合物化合物，包括 具有至少一个选自封端异氰酸酯基团和封端异硫氰酸酯基团的基团的重复单元、 具有至少一个选自羟基和羧基的基团的重复单元，以及 由下式(1)表示的重复单元，其中 具有至少一个选自封端异氰基和封端异硫氰基的基团的重复单元在聚合物化合物中的含量为 1%（以摩尔计）或以上，当上述聚合物化合物中所含所有重复单元的总含量为 100%（以摩尔计）时，其含量为 30%（以摩尔计）或以下： 在式 (1) 中，R2、R2 和 R3 各自独立地代表氢原子或甲基。
• The ‘Baylis - Hillman Reaction’ mechanism and applications revisited
  作者：Yves Fort、Marie Christine Berthe、Paul Caubere

  DOI：10.1016/s0040-4020(01)88227-2

  日期：1992.1

  It is shown that reaction of aryl, benzyl, alkyl and functionalised alkyl acrylic esters with benzaldehyde, in the presence of 1,4-diazabicyclo[2.2.2] octane, strongly depends upon the electronic and steric effects of the ester part. This influence is also observed in condensation of furfuraldehyde. Moreover, for the first time, it is shown that the overall condensation is equilibrated.
• POLYMER COMPOUND, FILM OBTAINED BY HARDENING THIS POLYMER COMPOUND AND ELECTRONIC DEVICE COMPRISING THIS FILM
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20190211123A1

  公开（公告）日：2019-07-11

  A polymer compound comprising a repeating unit having at least one group selected from the group consisting of a blocked isocyanato group and a blocked isothiocyanato group, a repeating unit having at least one group selected from the group consisting of a hydroxy group and a carboxy group and a repeating unit represented by the following formula (1), wherein the content of the repeating unit having at least one group selected from the group consisting of a blocked isocyanato group and a blocked isothiocyanato group in the polymer compound is 1% by mol or more and 30% by mol or less when the total content of all repeating units contained in the above-described polymer compound is taken as 100% by mol: in the formula (1), R 2 , R 2 and R 3 each independently represent a hydrogen atom or a methyl group.
• POLYMER COMPOUND, COMPOSITION, INSULATING LAYER, AND ORGANIC THIN FILM TRANSISTOR
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：US20210024674A1

  公开（公告）日：2021-01-28

  Provided is an organic thin film transistor having a high carrier mobility. Provided is a polymer compound, including: a repeating unit represented by the following formula (1); and at least two repeating units, the repeating units being at least one selected from the group consisting of a repeating unit having a blocked isocyanato group and a repeating unit having a blocked isothiocyanato group, wherein, in formula (1), R 1 is a hydrogen atom or a methyl group; R is a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms; Rf is a fluorine atom or a monovalent organic group including a fluorine atom; R a is a divalent organic group having 1 to 20 carbon atoms, and a hydrogen atom in the divalent organic group may be substituted with a fluorine atom; X is an oxygen atom or a group represented by —NR 7 —; R 7 is a hydrogen atom or a monovalent organic group having 1 to 20 carbon atoms; a is an integer of 0 to 20; and m is an integer of 1 to 5.