N-pyridin-3-yl-2-[2-(pyridin-3-ylcarbamoyl)phenyl]benzamide | 348606-10-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-pyridin-3-yl-2-[2-(pyridin-3-ylcarbamoyl)phenyl]benzamide
• CAS: 348606-10-0
• 化学式: C₂₄H₁₈N₄O₂
• 分子量: 394.433
• InChiKey: QQIJEUKFMILISR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  30
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  84
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  9-氯甲基蒽 、 N-pyridin-3-yl-2-[2-(pyridin-3-ylcarbamoyl)phenyl]benzamide 以 N,N-二甲基甲酰胺 、 乙腈 为溶剂， 反应 36.0h， 以22%的产率得到
  参考文献：
  名称：

  Pyridinium amide-based simple synthetic receptor for selective recognition of dihydrogenphosphate

  摘要：

  A new fluorescent receptor 1 built on biphenyl motif has been designed and synthesized Pyridinium amide moiety in 1 acts as binding site and shows selective complexanon of isophthalate and H2PO4 under the mastery of biphenyl spacer. Binding-induced increase in emission was used to determine the selectivity and sensitivity of I toward a series of anions such as different dicarboxylates, HSO4-, CIO4, and H2PO4. The binding characteristics were established by H-1 NMR, UV-vis, and fluorescence spectroscopic methods (C) 2009 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.tetlet.2009.09.043
• 作为产物：
  描述：

  3-氨基吡啶 、 2,2'-biphenyldicarboxylic acid dichloride 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以39%的产率得到N-pyridin-3-yl-2-[2-(pyridin-3-ylcarbamoyl)phenyl]benzamide
  参考文献：
  名称：

  Pyridinium amide-based simple synthetic receptor for selective recognition of dihydrogenphosphate

  摘要：

  A new fluorescent receptor 1 built on biphenyl motif has been designed and synthesized Pyridinium amide moiety in 1 acts as binding site and shows selective complexanon of isophthalate and H2PO4 under the mastery of biphenyl spacer. Binding-induced increase in emission was used to determine the selectivity and sensitivity of I toward a series of anions such as different dicarboxylates, HSO4-, CIO4, and H2PO4. The binding characteristics were established by H-1 NMR, UV-vis, and fluorescence spectroscopic methods (C) 2009 Elsevier Ltd All rights reserved

  DOI：

  10.1016/j.tetlet.2009.09.043

文献信息

• Pyridinium amide-based simple synthetic receptor for selective recognition of dihydrogenphosphate
  作者：Kumaresh Ghosh、Avik Ranjan Sarkar、Amarendra Patra

  DOI：10.1016/j.tetlet.2009.09.043

  日期：2009.11

  A new fluorescent receptor 1 built on biphenyl motif has been designed and synthesized Pyridinium amide moiety in 1 acts as binding site and shows selective complexanon of isophthalate and H2PO4 under the mastery of biphenyl spacer. Binding-induced increase in emission was used to determine the selectivity and sensitivity of I toward a series of anions such as different dicarboxylates, HSO4-, CIO4, and H2PO4. The binding characteristics were established by H-1 NMR, UV-vis, and fluorescence spectroscopic methods (C) 2009 Elsevier Ltd All rights reserved