1-Phenylpropyl-phenylethylacetat | 151292-53-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Phenylpropyl-phenylethylacetat
• 英文别名: 1-Phenylpropyl 2-phenylacetate
• CAS: 151292-53-4
• 化学式: C₁₇H₁₈O₂
• 分子量: 254.329
• InChiKey: JVXCRCNAUQKBTL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-Phenylpropyl-phenylethylacetat 以 乙腈 为溶剂， 生成 (R)-(+)-1-苯基-1-丙醇 、 S(-)-1-苯基-1-丙醇
  参考文献：
  名称：

  Pen G acylase catalyzed resolution of phenylacetate esters of secondary alcohols

  摘要：

  Penicillin G acylase from E. coli (E.C. 3.5.1.11.) immobilized on Eupergit C is used for the kinetic resolution of phenyl acetate esters of secondary alcohols of pharmaceutical interest.

  DOI：

  10.1016/s0957-4166(00)80148-2

文献信息

• PENICILLIN-G ACYLASES
  申请人：BEHROUZIAN BEHNAZ

  公开号：US20100143968A1

  公开（公告）日：2010-06-10

  The present disclosure relates to engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes.
• US8247192B2
  申请人：——

  公开号：US8247192B2

  公开（公告）日：2012-08-21
• US8569013B2
  申请人：——

  公开号：US8569013B2

  公开（公告）日：2013-10-29
• [EN] PENICILLIN-G ACYLASES<br/>[FR] PÉNICILLINE G ACYLASES
  申请人：CODEXIS INC

  公开号：WO2010054319A2

  公开（公告）日：2010-05-14

  The present disclosure relates to engineered penicillin G acylase (PGA) enzymes having improved properties, polynucleotides encoding such enzymes, compositions including the enzymes, and methods of using the enzymes.
• Pen G acylase catalyzed resolution of phenylacetate esters of secondary alcohols
  作者：E. Baldaro、P. D'Arrigo、G. Pedrocchi-Fantoni、C.M. Rosell、S. Servi、A. Tagliani、M. Terreni

  DOI：10.1016/s0957-4166(00)80148-2

  日期：1993.5

  Penicillin G acylase from E. coli (E.C. 3.5.1.11.) immobilized on Eupergit C is used for the kinetic resolution of phenyl acetate esters of secondary alcohols of pharmaceutical interest.