(+/-)-cis-N-Boc-4-methyl-pipecolinic acid | 187752-72-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (+/-)-cis-N-Boc-4-methyl-pipecolinic acid
• 英文别名: (2R,4S)-4-methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-2-carboxylic acid
• CAS: 187752-72-3
• 化学式: C₁₂H₂₁NO₄
• 分子量: 243.3
• InChiKey: LTNNUMKAWAGPIS-DTWKUNHWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  66.8
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Hemiasterlin Derivatives and Uses Thereof
  申请人：Campagna Silvio A.

  公开号：US20080108820A1

  公开（公告）日：2008-05-08

  The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R 1 -R 7 , X 1 , X 2 , R, Q, and n are as defined herein.
• HEMIASTERLIN DERIVATIVES AND USES THEREOF IN THE TREATMENT OF CANCER
  申请人：KOWALCZYK James J.

  公开号：US20100063095A1

  公开（公告）日：2010-03-11

  The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of cancer, wherein R 1 -R 7 , X 1 , X 2 , R, Q, and n are as defined herein.
• US7585976B2
  申请人：——

  公开号：US7585976B2

  公开（公告）日：2009-09-08
• US8129407B2
  申请人：——

  公开号：US8129407B2

  公开（公告）日：2012-03-06