1-[4-(4-methoxybenzyloxy)phenyl]cyclobutanecarbonitrile | 1010817-75-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1-[4-(4-methoxybenzyloxy)phenyl]cyclobutanecarbonitrile
• 英文别名: 1-[4-[(4-Methoxyphenyl)methoxy]phenyl]cyclobutane-1-carbonitrile
• CAS: 1010817-75-0
• 化学式: C₁₉H₁₉NO₂
• 分子量: 293.365
• InChiKey: YTRYABSXZUXUMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  22
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.32
• 拓扑面积：
  42.2
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• SYNTHESIS, METHODS OF USING, AND COMPOSITIONS OF CYCLOALKYLMETHYLAMINES
  申请人：Bhat Laxminarayan

  公开号：US20080139663A1

  公开（公告）日：2008-06-12

  The present invention provides novel cycloalkylmethylamine analogs, and methods of preparing cycloalkylmethylamine analogs. The present invention also provides methods of using cycloalkylmethylamine analogs and compositions of cycloalkylmethylamine analogs. The pharmaceutical compositions of the compounds of the present invention can be advantageously used for treating and/or preventing obesity and obesity related co-morbid indications.

  本发明提供了新型的环烷甲基胺类似物，以及制备环烷甲基胺类似物的方法。本发明还提供了使用环烷甲基胺类似物的方法和环烷甲基胺类似物的组合物。本发明化合物的制药组合物可以优势地用于治疗和/或预防肥胖和肥胖相关的合并症。
• Methods of Using Cycloalkylmethylamines
  申请人：Bhat Laxminarayan

  公开号：US20110263704A1

  公开（公告）日：2011-10-27

  The present invention provides novel cycloalkylmethylamine analogs, and methods of preparing cycloalkylmethylamine analogs. The present invention also provides methods of using cycloalkylmethylamine analogs and compositions of cycloalkylmethylamine analogs. The pharmaceutical compositions of the compounds of the present invention can be advantageously used for treating and/or preventing obesity and obesity related co-morbid indications.

  本发明提供了新型环烷基甲胺类似物和制备环烷基甲胺类似物的方法。本发明还提供了使用环烷基甲胺类似物和环烷基甲胺类似物组成物的方法。本发明的化合物制药组合物可以优势地用于治疗和/或预防肥胖和肥胖相关的共病症。
• Cycloalkylmethylamines
  申请人：Bhat Laxminarayan

  公开号：US20110263888A1

  公开（公告）日：2011-10-27

  The present invention provides novel cycloalkylmethylamine analogs, and methods of preparing cycloalkylmethylamine analogs. The present invention also provides methods of using cycloalkylmethylamine analogs and compositions of cycloalkylmethylamine analogs. The pharmaceutical compositions of the compounds of the present invention can be advantageously used for treating and/or preventing obesity and obesity related co-morbid indications.

  本发明提供了新型环烷基甲基胺类似物，以及制备环烷基甲基胺类似物的方法。本发明还提供了使用环烷基甲基胺类似物的方法和环烷基甲基胺类似物的组成物。本发明化合物的制药组合物可以优势地用于治疗和/或预防肥胖及其相关的共病症。
• SYNTHESIS, METHODS OF USING, AND COMPOSITIONS OF CYCLOBUTYLMETHYLAMINES
  申请人：Reviva Pharmaceuticals, Inc.

  公开号：EP2066329B1

  公开（公告）日：2017-09-06
• US7989500B2
  申请人：——

  公开号：US7989500B2

  公开（公告）日：2011-08-02