2-(3-nitro-phenoxy)-phenyl isocyanate | 118477-39-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(3-nitro-phenoxy)-phenyl isocyanate
• 英文别名: 2-(3-Nitro-phenoxy)-phenylisocyanat
• CAS: 118477-39-7
• 化学式: C₁₃H₈N₂O₄
• 分子量: 256.218
• InChiKey: HYMXCKASSLOCRH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.35
• 重原子数：
  19.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  81.8
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  2-(3-nitro-phenoxy)-phenyl isocyanate 在 盐酸 、 一水合肼 、 溶剂黄146 作用下， 反应 2.0h， 生成 (2-amino-phenyl)-(3-amino-phenyl)-ether
  参考文献：
  名称：

  Expression of human hepatitis C virus core antigen in tobacco plants by tobacco mosaic virus-based vector system

  摘要：

  Tobacco mosaic virus (TMV) has the potential to highly express foreign gene. A novel TMV-based in trans expression system was constructed. A TMV mutant TSHc had its coat protein replaced with hepatitis C virus (HCV) core antigen gene. Another TMV mutant TSBD was replicase-detective. Coinfection of the two mutants could cause systemic infection in tobacco plants by in trans complementation of their functions. TSHc could effectively replicate and assemble to viral particles, which were a little longer than that of wild-type TMV. HCV core antigen was expressed in whole tobacco plants. A similar expression lever of HCV core antigen was detected on serial passages, which suggested that this viral expression system be stable.

  DOI：

  10.1007/bf02884901