1,2-Ethanediamine, N,N'-bis[(2,5-dimethoxyphenyl)methylene]- | 110662-23-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1,2-Ethanediamine, N,N'-bis[(2,5-dimethoxyphenyl)methylene]-
• 英文别名: 1-(2,5-dimethoxyphenyl)-N-[2-[(2,5-dimethoxyphenyl)methylideneamino]ethyl]methanimine
• CAS: 110662-23-2
• 化学式: C₂₀H₂₄N₂O₄
• 分子量: 356.422
• InChiKey: OAASQSSBLPZNGY-UHFFFAOYSA-N

物化性质

• 沸点：
  536.1±50.0 °C(Predicted)
• 密度：
  1.08±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  26
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  61.6
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  zinc(II) chloride 、 1,2-Ethanediamine, N,N'-bis[(2,5-dimethoxyphenyl)methylene]- 以 甲醇 、 氯仿 为溶剂， 反应 2.0h， 以86%的产率得到
  参考文献：
  名称：

  Synthesis, characterization and computational studies of zinc(II)-halide complexes with a bidentate schiff base ligand (2,5-MeO-ba)2En: The crystal structure of (2,5-MeO-ba)2En

  摘要：

  In this study four coordinated complexes of zinc(II) halides with a new symmetrical bidentate Schiff base ligand (2,5-MeO-ba)(2)En are synthesized and characterized. The metal to ligand ratio of the complexes is found to be 1:1 with the formula of Zn((2,5-MeO-ba)(2)En)X-2 (X = Cl (1), Br (2), I (3)). The crystal structure of the Schiff base ligand (2,5-MeO-ba)(2)En is determined by X-ray crystallography from single crystal data. Also, the optimized geometries of the Schiff base ligand (2,5-MeO-ba)(2)En and its zinc(II) complexes are calculated using the density functional theory method (B3LYP/6-31G). The obtained structural parameters of (2,5-MeO-ba)(2)En are in agreement with the experimental data.

  DOI：

  10.1134/s0022476613040161
• 作为产物：
  描述：

  2,5-二甲氧基苯甲醛 、 乙二胺 以 甲醇 为溶剂， 反应 1.5h， 以91%的产率得到1,2-Ethanediamine, N,N'-bis[(2,5-dimethoxyphenyl)methylene]-
  参考文献：
  名称：

  Synthesis, characterization and computational studies of zinc(II)-halide complexes with a bidentate schiff base ligand (2,5-MeO-ba)2En: The crystal structure of (2,5-MeO-ba)2En

  摘要：

  In this study four coordinated complexes of zinc(II) halides with a new symmetrical bidentate Schiff base ligand (2,5-MeO-ba)(2)En are synthesized and characterized. The metal to ligand ratio of the complexes is found to be 1:1 with the formula of Zn((2,5-MeO-ba)(2)En)X-2 (X = Cl (1), Br (2), I (3)). The crystal structure of the Schiff base ligand (2,5-MeO-ba)(2)En is determined by X-ray crystallography from single crystal data. Also, the optimized geometries of the Schiff base ligand (2,5-MeO-ba)(2)En and its zinc(II) complexes are calculated using the density functional theory method (B3LYP/6-31G). The obtained structural parameters of (2,5-MeO-ba)(2)En are in agreement with the experimental data.

  DOI：

  10.1134/s0022476613040161

文献信息

• Copper(II) Schiff base complexes and their mixed thin layers with ZnO nanoparticles
  作者：MAGDALENA BARWIOLEK、ROBERT SZCZĘSNY、EDWARD SZŁYK

  DOI：10.1007/s12039-016-1116-y

  日期：2016.7

  ethylenediamine were structurally and spectroscopically characterized. Thin layers of Cu(II) complexes were deposited on Si(111) or ZnO/Si(111) by a spin coating method. The Cu(II) layers exhibited fluorescence bands between 462 and 503 nm. In the Cu(II)complex/ZnO/Si layers, quenching of the emission band from ZnO at 440 nm (λex=330 nm) was noted.

  获得了具有乙二胺（en）和2-吡啶吡啶甲醛（pyca），2,5-二甲氧基苯甲醛（dmbaH）或4-咪唑甲醛（4Him）的席夫碱的Cu（II）配合物，并通过元素分析，UV-VIS和IR进行了研究光谱。使用简单的均相沉淀法以乙酸锌为起始原料合成氧化锌。通过旋涂法将研究的Cu（II）配合物薄层沉积在Si（111）或ZnO / Si（111）衬底上，并用扫描电子显微镜（SEM / EDS），原子力显微镜（AFM）和荧光光谱。对于Cu（II）层，在462和503 nm之间观察到由于配体内跃迁而引起的最强荧光带。薄层的荧光强度与旋转速度相关。在[Cu（II）（en（4Him）2）氯2 ]（2A）/氧化锌/ Si和[铜（烯（dmbaH）2）氯2 ]（3A）/氧化锌/硅层由ZnO发射带的在440nm淬火（λ EX = 330nm处注意到与各种内在或外在的晶格缺陷有关。 从乙二胺获得的具有席夫碱的新型铜（I
• Synthesis and antiinflammatory, analgesic activity of 3,3′-(1,2-Ethanediyl)-bis[2-aryl-4-thiazolidinone] chiral compounds. Part 10
  作者：M.G Vigorita、R Ottanà、F Monforte、R Maccari、A Trovato、M.T Monforte、M.F Taviano

  DOI：10.1016/s0960-894x(01)00476-0

  日期：2001.11

  In this note, the synthesis and structure-activity relationships of a new series of 2R,2'R/2S,2'S and 2R,2'S-meso 3,3'-(1,2-ethanediyl)-bis[2-aryl-4-thiazolidinones] are described. Antiinflammatory activity was investigated by the carrageenin-induced paw edema test and analgesic activity by acetic acid writhing and hot plate tests in rats. All compounds displayed ulcerogenic effects and acute toxicity

  在此说明中，新系列的2R，2'R / 2S，2'S和2R，2'S-间消旋3,3'-（1,2-乙二基）-双[2-芳基-描述了4-噻唑烷酮。通过角叉菜胶诱导的爪水肿试验研究了抗炎活性，并且通过乙酸扭结法和热板试验研究了大鼠的镇痛活性。所有化合物均显示出致溃疡作用和急性毒性，远低于消炎痛和苯基丁a。中观异构体（b）显示出比相应的外消旋体（a）更好的药理特性。在药理学特征上，立体异构碳上的芳基的甲氧基取代模式通常是最有利的。
• Synthesis, characterization and computational studies of zinc(II)-halide complexes with a bidentate schiff base ligand (2,5-MeO-ba)2En: The crystal structure of (2,5-MeO-ba)2En
  作者：A. D. Khalaji、H. Mighani、M. Gholinejad、G. Grivani、S. Jalali Akerdi、K. Fejfarova、M. Dusek

  DOI：10.1134/s0022476613040161

  日期：2013.7

  In this study four coordinated complexes of zinc(II) halides with a new symmetrical bidentate Schiff base ligand (2,5-MeO-ba)(2)En are synthesized and characterized. The metal to ligand ratio of the complexes is found to be 1:1 with the formula of Zn((2,5-MeO-ba)(2)En)X-2 (X = Cl (1), Br (2), I (3)). The crystal structure of the Schiff base ligand (2,5-MeO-ba)(2)En is determined by X-ray crystallography from single crystal data. Also, the optimized geometries of the Schiff base ligand (2,5-MeO-ba)(2)En and its zinc(II) complexes are calculated using the density functional theory method (B3LYP/6-31G). The obtained structural parameters of (2,5-MeO-ba)(2)En are in agreement with the experimental data.