| 1334426-12-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• CAS: 1334426-12-8
• 化学式: C₁₆H₂₁NO
• 分子量: 243.349
• InChiKey: JQPUEWMTFOLHCV-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  在 碘 、 碳酸氢钠 作用下， 以 二氯甲烷 为溶剂， 以74%的产率得到(3E)-2-tert-butyl-3-(1-iodobutylidene)isoindol-1-one
  参考文献：
  名称：

  Gold- and Iodine-Mediated Internal Oxygen Transfer of Nitrone- and Sulfoxide-Functionalized Alkynes

  摘要：

  Intramolecular oxygen transfer of nitrone- and sulfoxide-alkynes was achieved using a catalytic amount of Au(I) and a stoichiometric amount of iodine. The Au(I)-catalyzed cyclization of a nitrone-terminal alkyne afforded a cyclic iminoester, while cyclization of analogous nitrone-internal alkynes yielded aldehyde enones. The I-2-mediated cyclization of nitrone-alkynes afforded iodinated gamma-lactams and the I-2-mediated internal redox of the closely related sulfoxide alkynes gave diketones functionalized with a thoiether.

  DOI：

  10.1021/jo201347r