2,2'-[2,3-naphthalenebis(oxy)]-bis(N,N-diisopropyl(acetamide)) | 868069-37-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 萘
• 英文名称: 2,2'-[2,3-naphthalenebis(oxy)]-bis(N,N-diisopropyl(acetamide))
• 英文别名: 2,2'-[2,3-naphthylenebis(oxy)]-bis(N,N-diisopropyl(acetamide))；2,2'-(2,3-naphthylenebisoxy)bis(N,N-diisopropylacetamide)；2-[3-[2-[di(propan-2-yl)amino]-2-oxoethoxy]naphthalen-2-yl]oxy-N,N-di(propan-2-yl)acetamide
• CAS: 868069-37-8
• 化学式: C₂₆H₃₈N₂O₄
• 分子量: 442.599
• InChiKey: GUQCFSQZSPSTAZ-UHFFFAOYSA-N

物化性质

• 沸点：
  587.8±40.0 °C(Predicted)
• 密度：
  1.071±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  32
• 可旋转键数：
  10
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  59.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,2'-[2,3-naphthalenebis(oxy)]-bis(N,N-diisopropyl(acetamide)) 、 europium(III) nitrate hexahydrate 以 乙酸乙酯 为溶剂， 以80%的产率得到[Eu(NO3)3(2,2'-[2,3-naphthalenebis(oxy)]-bis(N,N-diisopropyl(acetamide))]
  参考文献：
  名称：

  Terminal group effects on the fluorescence spectra of europium(III) nitrate complexes with a family of amide-based 2,3-dihydroxynaphthalene derivatives

  摘要：

  Three ligands 2,2'-[2,3-naphthylenebis(oxy)]-bis(N,N-diethyl(acetamide)) (U), 2,2'-[2,3-naphthylenebis(oxy)]-bis(NN-diisopropyl(acetamide)) (L-b) and 2,2'-[2,3-naphthylenebis(oxy)]-bis(NN-dibutyl(acetamide)) (L-c) and their europium(III) nitrate complexes were synthesized. The complexes were characterized by elemental analysis, IR, fluorescence spectroscopy and conductivity. The europium atoms are coordinated by O-atoms from C=O, Ar-O-C. With the difference of the ligands, the solid fluorescent intensities of the Eu complexes vary regularly. Some factors that influencing the fluorescent intensity were discussed. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2005.10.028
• 作为产物：
  描述：

  N,N-二异丙基氯乙酰胺 、 2,3-二羟基萘 在 potassium carbonate 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 11.0h， 以80%的产率得到2,2'-[2,3-naphthalenebis(oxy)]-bis(N,N-diisopropyl(acetamide))
  参考文献：
  名称：

  2，与2,2'-（2,3-亚萘基双氧基）-双（ N， N- 二异丙基乙酰胺 ）配合物的晶体结构和荧光性质

  摘要：

  制备并表征了硝酸euro与2,2'-（2,3-亚萘基双氧基）双（ N ， N-二异丙基乙酰胺 ）（ L ）的固体配合物 。研究了Eu（III）配合物的X射线晶体结构和溶剂依赖性荧光性质。

  DOI：

  10.1007/s00706-005-0459-8

文献信息

• Synthesis, Crystal Structure, and DNA-Binding Study on the Trinitrate{2,2′-[2,3-naphthylenebis(oxy)]-bis(<i>N</i>,<i>N</i>-diisopropyl(acetamide))} Gadolinium(III) Complex
  作者：Kewei Lei、Weisheng Liu、Xiaofeng Huang、Daqi Wang

  DOI：10.1248/cpb.54.1150

  日期：——

  A 2,2'-[2,3-naphthylenebis(oxy)]-bis(N,N-diisopropyl(acetamide)) ligand (L) and its Gd(III) complex have been prepared and characterized. The crystal and molecular structure of the complex was determined by single-crystal X-ray diffraction. The interactions of complex with calf thymus DNA were investigated by UV-vis, fluorescence and viscosity measurements. Experimental results indicated that the complex

  制备并表征了2,2'-[2,3-亚萘基双（氧基）]-双（N，N-二异丙基（乙酰胺））配体（L）及其Gd（III）配合物。通过单晶X射线衍射确定配合物的晶体和分子结构。通过UV-vis，荧光和粘度测量研究了复合物与小牛胸腺DNA的相互作用。实验结果表明，该复合物可以通过嵌入方式与DNA结合。它的固有结合常数为1.03 x 10（6）M（-1）。
• Crystal Structure and Fluorescence Properties of Europium Complex with 2,2′-(2,3-Naphthylenebisoxy)-bis(N,N-diisopropylacetamide)
  作者：Kewei Lei、Weisheng Liu、Kaibei Yu

  DOI：10.1007/s00706-005-0459-8

  日期：2006.4

  Solid complex of europium nitrate with 2,2′-(2,3-naphthylenebisoxy)bis( N , N -diisopropylacetamide) ( L ) has been prepared and characterized. The X-ray crystal structure and the solvent dependent fluorescence properties of the Eu(III) complex were investigated.

  制备并表征了硝酸euro与2,2'-（2,3-亚萘基双氧基）双（ N ， N-二异丙基乙酰胺 ）（ L ）的固体配合物 。研究了Eu（III）配合物的X射线晶体结构和溶剂依赖性荧光性质。
• Terminal group effects on the fluorescence spectra of europium(III) nitrate complexes with a family of amide-based 2,3-dihydroxynaphthalene derivatives
  作者：Ke-Wei Lei、Wei-Sheng Liu

  DOI：10.1016/j.saa.2005.10.028

  日期：2006.9

  Three ligands 2,2'-[2,3-naphthylenebis(oxy)]-bis(N,N-diethyl(acetamide)) (U), 2,2'-[2,3-naphthylenebis(oxy)]-bis(NN-diisopropyl(acetamide)) (L-b) and 2,2'-[2,3-naphthylenebis(oxy)]-bis(NN-dibutyl(acetamide)) (L-c) and their europium(III) nitrate complexes were synthesized. The complexes were characterized by elemental analysis, IR, fluorescence spectroscopy and conductivity. The europium atoms are coordinated by O-atoms from C=O, Ar-O-C. With the difference of the ligands, the solid fluorescent intensities of the Eu complexes vary regularly. Some factors that influencing the fluorescent intensity were discussed. (c) 2005 Elsevier B.V. All rights reserved.