4-[1-(2-tert-butoxycarbonylaminoethyl)piperidin-4-yl]butyric acid methyl ester | 845754-03-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 4-[1-(2-tert-butoxycarbonylaminoethyl)piperidin-4-yl]butyric acid methyl ester
• 英文别名: Methyl 4-(1-(2-((tert-butoxycarbonyl)amino)ethyl)piperidin-4-yl)butanoate；methyl 4-[1-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethyl]piperidin-4-yl]butanoate
• CAS: 845754-03-2
• 化学式: C₁₇H₃₂N₂O₄
• 分子量: 328.452
• InChiKey: VFNJTLAXYAHQRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  23
• 可旋转键数：
  10
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  67.9
• 氢给体数：
  1
• 氢受体数：
  5

文献信息

• Methods of reducing risk of infection from pathogens
  申请人：Johnson R. Michael

  公开号：US20050090505A1

  公开（公告）日：2005-04-28

  Prophylactic treatment methods are provided for protection of individuals and/or populations against infection from airborne pathogens. In particular, prophylactic treatment methods are provided comprising administering a sodium channel blocker or pharmaceutically acceptable salts thereof to one or more members of a population at risk of exposure to or already exposed to one or more airborne pathogens, either from natural sources or from intentional release of pathogens into the environment.

  提供了预防性治疗方法，以保护个人和/或人群免受空气传播病原体的感染。特别是，提供了预防性治疗方法，包括向处于接触或已经接触到一个或多个空气传播病原体的风险人群中的一个或多个成员，从自然来源或故意释放病原体进入环境中，给予钠通道阻滞剂或其药学上可接受的盐。
• Cyclic pyrazinoylguanidine sodium channel blockers
  申请人：Johnson R. Michael

  公开号：US20050059676A1

  公开（公告）日：2005-03-17

  The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.

  本发明涉及钠通道阻滞剂。本发明还包括使用这些创新的钠通道阻滞剂进行多种治疗方法。
• CYCLIC PYRAZINOYLGUANIDINE SODIUM CHANNEL BLOCKERS
  申请人：JOHNSON R. Michael

  公开号：US20080103148A1

  公开（公告）日：2008-05-01

  The present invention relates to sodium channel blockers. The present invention also includes a variety of methods of treatment using these inventive sodium channel blockers.

  本发明涉及钠通道阻滞剂。本发明还包括使用这些创新的钠通道阻滞剂的各种治疗方法。
• METHODS OF REDUCING RISK OF INFECTION FROM PATHOGENS
  申请人：Parion Sciences, Inc.

  公开号：EP1656096A2

  公开（公告）日：2006-05-17
• EP1670474A4
  申请人：——

  公开号：EP1670474A4

  公开（公告）日：2008-08-06