Dimethyl-[4-(5-nitro-benzo[c]isothiazol-3-ylazo)-phenyl]-amine | 79542-35-1

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: Dimethyl-[4-(5-nitro-benzo[c]isothiazol-3-ylazo)-phenyl]-amine
• 英文别名: N,N-dimethyl-4-[(5-nitro-2,1-benzothiazol-3-yl)diazenyl]aniline
• CAS: 79542-35-1
• 化学式: C₁₅H₁₃N₅O₂S
• 分子量: 327.367
• InChiKey: XFCNDYOMNIYAFX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  23
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  115
• 氢给体数：
  0
• 氢受体数：
  7

文献信息

• FLUORESCENT PROBES FOR DNA DETECTION BY HYBRIDIZATION WITH IMPROVED SENSITIVITY AND LOW BACKGROUND
  申请人：Lokhov Sergey

  公开号：US20080293586A1

  公开（公告）日：2008-11-27

  Minor groove binder-oligonucleotide probes are provided along with methods for their use wherein the probes have an attached fluorophore which, in an unhybridized form exhibits very low background signal.

  提供了微小沟结合剂寡核苷酸探针以及其使用方法，其中探针具有附加的荧光物质，未杂交形式的荧光物质信号非常低。
• FLUORESCENT QUENCHING DETECTING REAGENTS AND METHODS
  申请人：Reed Michael W.

  公开号：US20100174058A1

  公开（公告）日：2010-07-08

  Oligonucleotide probes containing two labels are provided and are useful in hybridization assays. The probes can also contain a minor groove binding group.

  提供了含有两个标签的寡核苷酸探针，适用于杂交检测。这些探针还可以包含一个次级沟结合基团。
• Real-time linear detection probes: sensitive 5'-minor groove binder-containing probes for PCR analysis
  申请人：Afonina A. Irina

  公开号：US20070003957A1

  公开（公告）日：2007-01-04

  Oligonucleotide probes/conjugates are provided along with method for their use in assays to monitor amplification wherein the signal produced does not rely on 5′ nuclease digestion.
• AMPLIFICATION METHODS
  申请人：MAHONEY WALT

  公开号：US20080248474A1

  公开（公告）日：2008-10-09

  Methods are provided for amplification and monitoring of oligonucleotide amplification in which a primer has an overlap with one or more bases of a detection probe.
• SINGLE NUCLEOTIDE POLYMORPHISM ANALYSIS OF HIGHLY POLYMORPHIC TARGET SEQUENCES
  申请人：Belousov Yevgeniy

  公开号：US20090087922A1

  公开（公告）日：2009-04-02

  Methods and probes are provided for the analysis of target sequences having two or more polymorphisms wherein one of the polymorphisms is to be distinguished and another polymorphism is to be masked.