1-Chloro-4,5-bis(diphenylphosphinyl)pentane | 130304-88-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Chloro-4,5-bis(diphenylphosphinyl)pentane
• 英文别名: Phosphine oxide, [1-(3-chloropropyl)-1,2-ethanediyl]bis[diphenyl-；[(5-chloro-2-diphenylphosphorylpentyl)-phenylphosphoryl]benzene
• CAS: 130304-88-0
• 化学式: C₂₉H₂₉ClO₂P₂
• 分子量: 506.949
• InChiKey: PPLLYFHVOGNPJV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.1
• 重原子数：
  34
• 可旋转键数：
  10
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-氯甲基四氢呋喃 在 氢氧化钾 、 五氯化磷 作用下， 以 氯仿 、 二甲基亚砜 为溶剂， 反应 3.83h， 生成 1-Chloro-4,5-bis(diphenylphosphinyl)pentane
  参考文献：
  名称：

  Reversible nature of the opening of the tetrahydrofuran ring of diphenyl(2-tetrahydrofurylmethyl)phosphine oxide by the diphenylphosphinite anion

  摘要：

  The reaction of diphenyl (2-tetrahydrofurylmethyl)phosphine oxide with diphenylphosphonous acid in DMSO in the presence of KOH proceeds with opening of the tetrahydrofuran ring and leads to 4,5-bis(diphenylphosphinyl) pentanol. This product is converted to the starting oxide upon the reaction with diphenylvinylphosphine oxide. 4,5-Bis(diphenylphosphinyl) pentanol is converted to the corresponding tosylate. The action of alcoholates on this tosylate gives 1-ethoxy-4,5-bis(diphenylphosphinyl)pentane and 1-butoxy-1,5-bis(diphenylphosphinyl)pentane.

  DOI：

  10.1007/bf00962400

文献信息

• ANTOSHIN, A. EH.;XARITONOV, A. V.;TSVETKOV, E. N., IZV. AN CCCP. CEP. XIM.,(1990) N, S. 1421-1424
  作者：ANTOSHIN, A. EH.、XARITONOV, A. V.、TSVETKOV, E. N.

  DOI：——

  日期：——
• Reversible nature of the opening of the tetrahydrofuran ring of diphenyl(2-tetrahydrofurylmethyl)phosphine oxide by the diphenylphosphinite anion
  作者：A. �. Antoshin、A. V. Kharitonov、E. N. Tsvetkov

  DOI：10.1007/bf00962400

  日期：1990.6

  The reaction of diphenyl (2-tetrahydrofurylmethyl)phosphine oxide with diphenylphosphonous acid in DMSO in the presence of KOH proceeds with opening of the tetrahydrofuran ring and leads to 4,5-bis(diphenylphosphinyl) pentanol. This product is converted to the starting oxide upon the reaction with diphenylvinylphosphine oxide. 4,5-Bis(diphenylphosphinyl) pentanol is converted to the corresponding tosylate. The action of alcoholates on this tosylate gives 1-ethoxy-4,5-bis(diphenylphosphinyl)pentane and 1-butoxy-1,5-bis(diphenylphosphinyl)pentane.