1,5-di-O-acetyl-1-deuterio-2,3,4,6-tetra-O-methyl-D-galactitol | 64726-61-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,5-di-O-acetyl-1-deuterio-2,3,4,6-tetra-O-methyl-D-galactitol
• 英文别名: [(2S,3R,4S,5R)-5-acetyloxy-1-deuterio-2,3,4,6-tetramethoxyhexyl] acetate
• CAS: 64726-61-0
• 化学式: C₁₄H₂₆O₈
• 分子量: 323.348
• InChiKey: OVCJDQPBVXUBBF-GNOGWXPTSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  89.5
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  Me D-Gul 生成 1,5-di-O-acetyl-1-deuterio-2,3,4,6-tetra-O-methyl-D-galactitol
  参考文献：
  名称：

  DOARES, STEVEN H.;ALBERSHEIM, PETER;DARVILL, ALAN G., CARBOHYDR. RES., 210,(1991) C. 311-317

  摘要：

  DOI：

文献信息

• The structural characterization of the O-polysaccharide antigen of the lipopolysaccharide of Escherichia coli serotype O118 and its relation to the O-antigens of Escherichia coli O151 and Salmonella enterica O47
  作者：Leann L. MacLean、Yanhong Liu、Evgeny Vinogradov、Malcolm B. Perry

  DOI：10.1016/j.carres.2010.10.004

  日期：2010.12

  Mild acid hydrolysis of the lipopolysaccharide produced by Escherichiacoli O118:H16 standard strain (NRCC 6613) afforded an O-polysaccharide (O-PS) composed of d-galactose, 2-acetamidoylamino-2,6-dideoxy-L-galactose, 2-acetamido-2-deoxy-D-glucose, ribitol, and phosphate (1:1:1:1:1). From DOC-PAGE, sugar and methylation analyses, one- and two-dimensional NMR spectroscopy, capillary electrophoresis-mass

  大肠杆菌（Escherichiacoli）O118：H16标准菌株（NRCC 6613）产生的脂多糖的轻度酸水解得到了由d-半乳糖，2-乙酰氨基酰氨基-2,6-二脱氧-L-半乳糖2-组成的O-多糖（O-PS）。乙酰氨基-2-脱氧-D-葡萄糖，核糖醇和磷酸盐（1：1：1：1：1）。通过DOC-PAGE，糖和甲基化分析，一维和二维NMR光谱，毛细管电泳-质谱，水解和连续的Smith型高碘酸盐氧化研究，确定O-PS是具有以下特征的直链线性聚合物结构：[6）-α-d-Galp-（1→3）-α-L-FucpNAm-（1→3）-β-D-GlcpNAc-（1→3）-Rib-ol-5-P- （O→]（n）O-PS的结构与大肠杆菌O118的O抗原基因簇上报道的DNA数据一致，有趣的是，
• Formation of Homooligosaccharides Using Base-Promoted Glycosylation of Unprotected Glycosyl Fluorides
  作者：Andreas Steinmann、Julian Thimm、Martin Matwiejuk、Joachim Thiem

  DOI：10.1021/ma100191d

  日期：2010.4.27

  Homooligomeric saccharides are of general interest with potential applications in chemical, pharmaceutical, and food industry as well as for materials with novel properties. This contribution describes a methodology of a base-promoted "single step self-oligomerization" of glycosyl fluorides as donors leading to oligomers with up to similar to 25 saccharide units. The influences of base and reaction time were examined. Linkage analysis of the corresponding alditol acetates by GC/MS allowed for calculation of average structural elements of oligomers.