methyl 2,5-dimethyl-4-oxo-1-phenyl-5-(phenylamino)-4,5-dihydro-1H-pyrrole-3-carboxylate | 1421687-91-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯啉
• 英文名称: methyl 2,5-dimethyl-4-oxo-1-phenyl-5-(phenylamino)-4,5-dihydro-1H-pyrrole-3-carboxylate
• CAS: 1421687-91-3
• 化学式: C₂₀H₂₀N₂O₃
• 分子量: 336.39
• InChiKey: OOAKTDQMMJRBLP-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  (E)-methyl 3-(phenylamino)but-2-enoate 、 乙腈 在 氧气 、 copper diacetate 作用下， 反应 0.25h， 以3%的产率得到methyl 2,5-dimethyl-4-oxo-1-phenyl-5-(phenylamino)-4,5-dihydro-1H-pyrrole-3-carboxylate
  参考文献：
  名称：

  Electrospray Ionization Mass Spectrometry Reveals an Unexpected Coupling Product in the Copper-Promoted Synthesis of Pyrazoles

  摘要：

  The reaction mechanism of the intermolecular oxidative formation of pyrazole 2 via a C-C/N-N bond-formation cascade of the enaminone 1 is investigated by means of ESI-MS. No direct reaction intermediates are observed; however, the formation of an unexpected imidazolid-3-one derivative X is observed that involves an oxidative dimerization of 1 in the presence of dioxygen. The derivative X is isolated and characterized by means of multidimensional H-1 and C-13 NMR spectroscopy.

  DOI：

  10.1021/om3010417