4-methyl-oxazolo[5,4-c]pyridine-2-thiol | 1202884-38-5

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: 4-methyl-oxazolo[5,4-c]pyridine-2-thiol
• 英文别名: 4-methyl-1H-[1,3]oxazolo[5,4-c]pyridine-2-thione
• CAS: 1202884-38-5
• 化学式: C₇H₆N₂OS
• 分子量: 166.203
• InChiKey: SQARKRGHAPZNQE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.1
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  66.2
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Benzooxazole, oxazolopyridine, benzothiazole and thiazolopyridine derivatives
  申请人：Binggeli Alfred

  公开号：US20070093521A1

  公开（公告）日：2007-04-26

  This invention is concerned with compounds of the formula wherein X, A, B, R 1 , R 2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

  本发明涉及以下式子的化合物：其中X、A、B、R1、R2和G的定义如说明书和权利要求中所述，并且其药学上可接受的盐。本发明还涉及含有这种化合物的制药组合物、它们的制备过程以及它们用于治疗和/或预防与调节SST受体亚型5相关的疾病的用途。
• BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES
  申请人：Binggeli Alfred

  公开号：US20090163517A1

  公开（公告）日：2009-06-25

  This invention is concerned with compounds of the formula wherein X, A, B, R 1 , R 2 and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.

  本发明涉及式中的化合物，其中X，A，B，R1，R2和G如说明书和权利要求所定义，并且其药学上可接受的盐。本发明还涉及含有这种化合物的制药组合物，以及用于治疗和/或预防与SST受体亚型5调节相关的疾病的方法。
• [EN] BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE AND THIAZOLOPYRIDINE DERIVATIVES<br/>[FR] DERIVES DE BENZOOXAZOLE, OXAZOLOPYRIDINE, BENZOTHIAZOLE ET THIAZOLOPYRIDINE
  申请人：HOFFMANN LA ROCHE

  公开号：WO2007025897A2

  公开（公告）日：2007-03-08

  [EN] This invention is concerned with compounds of the formula (I) wherein X, A, B, R¹, R² and G are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to then- use for the treatment and/or prevention of diseases which are associated with the modulation of SST receptors subtype 5.
  [FR] L'invention concerne des composés représentés par la formule (I) dans laquelle X, A, B, R¹, R² et G tels qu'ils sont définis dans le descriptif et les revendications, ainsi que leurs sels acceptables sur le plan pharmaceutique. Elle concerne également des compositions pharmaceutiques contenant ces composés, une méthode servant à les préparer et leur utilisation en thérapie et/ou prophylaxie de maladies associées à la modulation du sous-type 5 des récepteurs de SST.