1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose | 6380-97-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡喃
• 英文名称: 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose
• 英文别名: 5-hydroxy-2-hydroxymethyl-2,3-dihydro-pyran-4-one；2-hydroxymethyl-5-hydroxy-2,3-dihydro-4H-pyran-4-one；Kojisaeure；2,3-Dihydro-5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one；5-hydroxy-2-(hydroxymethyl)-2,3-dihydropyran-4-one
• CAS: 6380-97-8
• 化学式: C₆H₈O₄
• 分子量: 144.127
• InChiKey: ZXCYXCIWKAILMP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,5-脱水-d-果糖 以 水 为溶剂， 反应 0.5h， 生成 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose
  参考文献：
  名称：

  Method of efficiently producing Ascopyrone P

  摘要：

  公开号：

  EP1690859B1

文献信息

• ANTITUMOR AGENT
  申请人：Nihon Starch Co., Ltd.

  公开号：EP1686122A1

  公开（公告）日：2006-08-02

  There is provided an antitumor medicine comprising 1,5-D-anhydrofructose and/or ascopyrone. The antitumor medicine has effects of ascopyrone in inhibiting the growth and metastasis of tumors, is expected to inhibit inflammation and exerts an excellent effect on prognosis.

  本发明提供了一种抗肿瘤药物，它由 1,5-D-anhydrofructose 和/或 ascopyrone 组成。该抗肿瘤药物具有抗肿瘤酮抑制肿瘤生长和转移的作用，可望抑制炎症，并对预后产生良好的影响。
• METHOD OF EFFICIENTLY PRODUCING ASCOPYRONE P
  申请人：Nihon Starch Co., Ltd.

  公开号：EP1690859A1

  公开（公告）日：2006-08-16

  A method for producing ascopyrone P from 1,5-D-anhydrofructose efficiently is provided. The method produces ascopyrone P by heating a solution of 1,5-D-anhydrofructose at a pH of 10 or less and a temperature of 100°C or higher.

  提供了一种从 1,5-D-anhydrofructose 高效生产 ascopyrone P 的方法。该方法通过加热 1,5-D-anhydrofructose 溶液生产 ascopyrone P，溶液的 pH 值为 10 或更低，温度为 100°C 或更高。
• Efficient production method of ascopyrone p
  申请人：Yoshinaga Kazuhiro

  公开号：US20070077618A1

  公开（公告）日：2007-04-05

  A method for producing ascopyrone P from 1,5-D-anhydrofructose efficiently is provided. The method produces ascopyrone P by heating a solution of 1,5-D-anhydrofructose at a pH of 10 or less and a temperature of 100° C. or higher.
• Antitumor medicine
  申请人：Maruyama Ikurou

  公开号：US20070135517A1

  公开（公告）日：2007-06-14

  There is provided an antitumor medicine comprising 1,5-D-anhydrofructose and/or ascopyrone. The antitumor medicine has effects of ascopyrone in inhibiting the growth and metastasis of tumors, is expected to inhibit inflammation and exerts an excellent effect on prognosis.
• US7517981B2
  申请人：——

  公开号：US7517981B2

  公开（公告）日：2009-04-14