2,5-dimethyl-1,3,4-trihydroxybenzene | 4380-95-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: 2,5-dimethyl-1,3,4-trihydroxybenzene
• 英文别名: 3,6-dimethyl-1,2,4-benzenetriol；hydroxy-β-orcinol；3,6-dimethyl-benzene-1,2,4-triol；2.3.5-Trihydroxy-1.4-dimethyl-benzol；2.3.5-Trihydroxy-p-xylol；3,6-Dimethyl-benzen-1,2,4-triol；3,6-Dimethylbenzene-1,2,4-triol
• CAS: 4380-95-4
• 化学式: C₈H₁₀O₃
• 分子量: 154.166
• InChiKey: GSOSWVGCAPGSDU-UHFFFAOYSA-N

物化性质

• 熔点：
  158 °C
• 沸点：
  333.7±22.0 °C(Predicted)
• 密度：
  1.314±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.6
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  60.7
• 氢给体数：
  3
• 氢受体数：
  3

安全信息

• 海关编码：
  2907299090

反应信息

• 作为反应物：
  描述：

  2,5-dimethyl-1,3,4-trihydroxybenzene 在 硫酸 、 三氯化铁 作用下， 生成 2,5-二羟基-3,6-二甲基环己-2,5-二烯-1,4-二酮
  参考文献：
  名称：

  羟基醌的化学。第二部分 3,6-二甲基苯-1,2,4-三醇的自氧化

  摘要：

  对3,6-二甲基苯-1,2,4-三醇的自氧化的光谱学和动力学研究表明，第一阶段是通过半醌中间体进行的，从而得到羟基醌，二羟基联苯二醌和过氧化氢作为初始产物。羟基醌与碱的随后反应得到2，5-二羟基-3，6-二甲基苯醌和另外的过氧化氢。该反应与醌的二聚反应竞争，得到无色的化合物C 16 H 18 O 7，特别是在不存在氧气的情况下，将其还原为联苯二醌。由于羟基醌与碱性过氧化氢之间的反应使环戊烷衍生物进一步复杂化，使第二步更为复杂。

  DOI：

  10.1039/j39670000611
• 作为产物：
  描述：

  2,4-dihydroxy-3,6-dimethylbenzaldehyde 在 sodium hydroxide 、 双氧水 作用下， 生成 2,5-dimethyl-1,3,4-trihydroxybenzene
  参考文献：
  名称：

  On the problem of constructing intermediate trajectories in the theory of elastic-Earth rotation around a center of mass

  摘要：

  DOI：

  10.1134/1.1342447

文献信息

• Optically active compound and photosensitive resin composition
  申请人：——

  公开号：US20030211421A1

  公开（公告）日：2003-11-13

  A photoactive compound is used in combination with a photosensitizer, represented by the following formula (1): A −[( J ) m −( X-Pro )] n (1) wherein A represents a hydrophobic unit comprising at least one kind of hydrophobic groups selected from a hydrocarbon group and a heterocyclic group, J represents a connecting group, X-Pro represents a hydrophilic group protected by a protective group Pro which is removable by light exposure, m represents 0 or 1, and n represents an integer of not less than 1. The protective group Pro may be removable by light exposure in association with the photosensitizer (especially, a photo acid generator), or may be a hydrophobic protective group. The hydrophilic group may be a hydroxyl group or a carboxyl group. The photoactive compound has high sensitivity to a light source of short wavelength beams, for resist application, therefore, the photoactive compound is advantageously used for forming a pattern with high resolution.

  一种光活性化合物与光敏剂结合使用，由以下公式（1）表示： A −[( J ) m −( X-Pro )] n (1) 其中，A代表至少包括一种从烃基和杂环基中选择的疏水基的疏水单元，J代表连接基团，X-Pro代表由光照可去除的保护基团Pro保护的亲水基团，m代表0或1，n代表不少于1的整数。 保护基团Pro可以与光敏剂（特别是光酸发生剂）一起通过光照可去除，也可以是疏水保护基团。亲水基团可以是羟基或羧基。光活性化合物对短波长光源具有很高的敏感性，用于光刻应用，因此，该光活性化合物有利于形成具有高分辨率的图案。
• Total Synthesis of Peniphenones A–D via Biomimetic Reactions of a Common <i>o</i>-Quinone Methide Intermediate
  作者：Justin T. J. Spence、Jonathan H. George

  DOI：10.1021/acs.orglett.5b02902

  日期：2015.12.18

  The total synthesis of peniphenones A–D has been achieved via Michael reactions between appropriate nucleophiles and a common o-quinone methide intermediate. This strategy, which was based on a biosynthetic hypothesis, minimized the use of protecting groups and thus facilitated concise syntheses of the natural products. The most complex target, the benzannulated spiroketal peniphenone A, was synthesized

  苯甲酮A–D的总合成是通过适当的亲核试剂与常见的邻苯二甲酰甲基甲烷中间体之间的迈克尔反应实现的。基于生物合成假说的该策略最大程度地减少了保护基的使用，从而促进了天然产物的简洁合成。最复杂的靶标是苯并环的螺酮苯乙酮A，它是通过九个线性步骤由市售起始原料对映选择性合成的。
• TRIAZINE RING-CONTAINING POLYMER AND COMPOSITION FOR FILM FORMATION COMPRISING SAME
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US20140371367A1

  公开（公告）日：2014-12-18

  Provided is a triazine ring-containing hyperbranched polymer comprising the repeating unit structure represented by formula (1) and having one or more triazine ring terminals, said one or more triazine ring terminals being capped with a compound that differs from the diamine compound serving as the starting material for the polymer and has at least two active hydrogen groups. In addition to the polymer itself exhibiting high heat resistance, high transparency, a high refractive index, high light resistance, high solubility, and low volume shrinkage, it is also possible to use the polymer to provide a composition for film formation capable of yielding a thick film having high hardness. (In formula (1), R and R′ each independently represent a hydrogen atom, an alkyl group, an alkoxy group, an aryl group, or an aralkyl group, and Ar represents a divalent organic group containing an aromatic ring and/or a heterocyclic ring.)

  提供的是一种含有三嗪环的超支化聚合物，其重复单元结构由式（1）表示，并具有一个或多个三嗪环端基，其中，所述一个或多个三嗪环端基被与作为聚合物起始材料的二胺化合物不同的化合物封顶，该化合物具有至少两个活性氢基团。除了聚合物本身具有高耐热性、高透明度、高折射率、高耐光性、高溶解性和低体积收缩率之外，还可以使用该聚合物提供用于制备薄膜的组合物，该组合物能够产生具有高硬度的厚膜。（在式（1）中，R和R'各自独立地表示氢原子、烷基、烷氧基、芳基或芳烷基，Ar表示一个含有芳香环和/或杂环的二价有机基团。）
• AROMATIC POLYAMIDE AND FILM-FORMING COMPOSITION CONTAINING SAME
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US20150252147A1

  公开（公告）日：2015-09-10

  An aromatic polyamide, which is obtained by reacting a benzene tricarboxylic acid or a derivative thereof with a diamine compound in the presence of a terminally blocked compound having a crosslinkable group and a functional group that is reactive with a benzene tricarboxylic acid such as 1-amino-2-propanol or a derivative thereof as expressed by scheme (1), and which has a weight average molecular weight of 1,000-100,000 in terms of polystyrene as determined by gel permeation chromatography, has good solubility in organic solvents, while maintaining heat resistance and transparency. A thick film can be formed using a film-forming composition that contains this aromatic polyamide.

  一种芳香族聚酰胺，通过在末端阻断化合物的存在下，将苯三羧酸或其衍生物与一种含有可交联基团和与苯三羧酸反应的官能团的二胺化合物反应而获得，例如1-氨基-2-丙醇或其衍生物，如图1所示。其相对于聚苯乙烯的重均分子量在1000-100000之间，通过凝胶渗透色谱法测定。该聚酰胺在有机溶剂中具有良好的溶解性，同时保持耐热性和透明度。使用含有该芳香族聚酰胺的成膜组合物可以形成厚膜。
• FILM-FORMING COMPOSITION
  申请人：NISSAN CHEMICAL INDUSTRIES, LTD.

  公开号：US20160017145A1

  公开（公告）日：2016-01-21

  A film-forming composition that contains a tricarbonyl-benzene hyperbranched-polymer cross-linker and a triazine-containing hyperbranch, as shown for example in the formula, can form a thin film that excels in terms of hardness and heat tolerance and exhibits a reduced decrease in index of refraction despite the addition of the cross-linker.

  含有三羰基苯超支化聚合物交联剂和三嗪基超支化物的成膜组合物，例如公式所示，可以形成一种优异的硬度和耐热性的薄膜，并且尽管添加了交联剂，折射率的降低也相对减少。