2,3,5-Trimethyl-1,4-dioxan | 3973-27-1

• 分子结构分类: 有机化合物 - 有机杂环化合物
• 英文名称: 2,3,5-Trimethyl-1,4-dioxan
• 英文别名: 2,3,5-Trimethyl-1,4-dioxen；2,3,6-Trimethyl-1,4-diox-2-en；2,3,6-Trimethyl-1,4-dioxen-2；2,5,6-trimethyl-2,3-dihydro-[1,4]dioxine；p-Dioxin, 2,3-dihydro-2,5,6-trimethyl-；2,5,6-trimethyl-2,3-dihydro-1,4-dioxine
• CAS: 3973-27-1
• 化学式: C₇H₁₂O₂
• 分子量: 128.171
• InChiKey: DXHJFSAGRRQOGK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.71
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

文献信息

• [EN] BENZO-FUSED HETEROCYCLIC DERIVATIVES USEFUL AS AGONISTS OF GPR120<br/>[FR] DÉRIVÉS HÉTÉROCYCLIQUES À CONDENSATION BENZO UTILES EN TANT QU'AGONISTES DE GPR120
  申请人：JANSSEN PHARMACEUTICA NV

  公开号：WO2014159061A2

  公开（公告）日：2014-10-02

  The present invention is directed to benzo-fused heterocyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by GPR120. More particularly, the compounds of the present invention are agonists of GPR120, useful in the treatment of, such as for example, Type II diabetes mellitus.